A phase 2 trial of hydroxychloroquine in individuals at risk for rheumatoid arthritis
Background Individuals with serum elevations of anti‐cyclic citrullinated peptide (anti‐CCP) antibodies are at increased risk for future rheumatoid arthritis (RA). No pharmacologic interventions have been approved for the prevention of RA in such ‘at‐risk’ individuals. However, hydroxychloroquine (HCQ) is used without supporting clinical trial evidence.
Kevin D. Deane +33 more
wiley +1 more source
Printing-Path-Dominated Anisotropy in FDM-PEEK: Modulation by Build Orientation for Tensile and Shear Performance. [PDF]
Liu K, Chen W, Shan F, Wang H, Li K.
europepmc +1 more source
Abstract Three‐dimensional visualization technologies (3DVTs) in anatomy education are popular as they offer a cost‐effective and accessible alternative to cadaveric specimens. However, the literature presents conflicting results regarding the effectiveness of 3DVTs in facilitating learning compared with traditional models.
H. C. Kristy Cheung +3 more
wiley +1 more source
Surface Modification of Polyetheretherketone (PEEK) via Femtosecond Laser Microprocessing for Enhanced Bioactivity: A Preliminary Study. [PDF]
Angelova L +3 more
europepmc +1 more source
Blended and digital approaches in histology and pathology teaching: A scoping review
Abstract Histology and pathology education is evolving, driven by the integration of digital microscopy with other technological advances. Gaining insight into the impact of this transition, while understanding the perspectives of both students and educators, is important for improving teaching practices. This includes mapping teaching methods, digital
Eleonora Nava +3 more
wiley +1 more source
Comparative Evaluation of the Marginal Fit of Zirconia and Polyetheretherketone Copings Fabricated Using Computer-Aided Design and Computer-Aided Manufacturing (CAD/CAM) Technology: A Systematic Review and Meta-Analysis. [PDF]
Harimkar RL +5 more
europepmc +1 more source
Abstract Language is a major source of systemic inequities in science, particularly among scholars whose first language is not English. Studies have examined scientists' linguistic practices in specific contexts; few, however, have provided a global analysis of multilingualism in science. Using two major bibliometric databases (OpenAlex and Dimensions),
Carolina Pradier +2 more
wiley +1 more source
Is Ti-Coated PEEK Superior to PEEK for Lumbar and Cervical Fusion Procedures? A Systematic Review and Meta-Analysis. [PDF]
Kincaid J +11 more
europepmc +1 more source
Abstract Aims Children with primary immunodeficiency (PID) and secondary antibody deficiency (SAD) often require immunoglobulin replacement therapy due to low plasma immunoglobulin G (IgG) levels and recurrent infections. Existing pharmacokinetic models for immunoglobulin in PID patients predominantly focus on adults, with limited attention to ...
Iek Leng Cheng +4 more
wiley +1 more source
Assessment of the biomechanical performance of digitally manufactured space maintainers: a finite element analysis. [PDF]
Karahan M +4 more
europepmc +1 more source

