Results 41 to 50 of about 57,737 (292)

PEEP or No PEEP: That Is Not the Question [PDF]

, 1996
Generally, positive end-expiratory pressure (PEEP) is applied to improve oxygenation, and has been shown to improve gas exchange and lung compliance in acute lung injury, but it is not without risk.
Arthur S Slutsky, Jesús Villar
core   +3 more sources

Effect of Intraoperative High Positive End-Expiratory Pressure (PEEP) With Recruitment Maneuvers vs Low PEEP on Postoperative Pulmonary Complications in Obese Patients: A Randomized Clinical Trial.

Journal of the American Medical Association (JAMA), 2019
Importance An intraoperative higher level of positive end-expiratory positive pressure (PEEP) with alveolar recruitment maneuvers improves respiratory function in obese patients undergoing surgery, but the effect on clinical outcomes is uncertain ...
T. Bluth, A. Serpa, M. Schultz, P. Pelosi, Marcelo Gama de Abreu, Mohamed Ahmed Sayedalahl   +5 more
semanticscholar   +1 more source

Individualized PEEP to optimise respiratory mechanics during abdominal surgery: a pilot randomised controlled trial.

British Journal of Anaesthesia, 2020
BACKGROUND Higher intraoperative driving pressures (ΔP) are associated with increased postoperative pulmonary complications (PPC). We hypothesised that dynamic adjustment of PEEP throughout abdominal surgery reduces ΔP, maintains positive end-expiratory ...
A. Fernandez-Bustamante, J. Sprung, Robert A. Parker, K. Bartels, T. Weingarten, C. Kosour, B. Thompson, M. V. Vidal Melo   +7 more
semanticscholar   +1 more source

Advanced respiratory monitoring in COVID-19 patients: use less PEEP!

Critical Care, 2020
With the emergence of COVID-19 we are confronted with a new clinical picture of acute respiratory distress syndrome in the intensive care unit. In the majority of patients, the respiratory mechanics are very different from the “normal” ARDS patient.
L. Roesthuis, M. V. D. van den Berg, H. van der Hoeven   +2 more
semanticscholar   +1 more source

Evaluation of PEEP and prone positioning in early COVID-19 ARDS

EClinicalMedicine, 2020
Background In face of the Coronavirus Disease (COVID)-19 pandemic, best practice for mechanical ventilation in COVID-19 associated Acute Respiratory Distress Syndrome (ARDS) is intensely debated.
M. Mittermaier, P. Pickerodt, F. Kurth, L. B. de Jarcy, A. Uhrig, Carmen García, F. Machleidt, Panagiotis Pergantis, S. Weber, Yaosi Li, Astrid Breitbart, Felix Bremer, P. Knape, M. Dewey, F. Doellinger, S. Weber-Carstens, Arthur S Slutsky, W. Kuebler, N. Suttorp, H. Müller-Redetzky   +19 more
semanticscholar   +1 more source

Changes in shunt, ventilation/perfusion mismatch, and lung aeration with PEEP in patients with ARDS: a prospective single-arm interventional study

Critical Care, 2020
Background Several studies have found only a weak to moderate correlation between oxygenation and lung aeration in response to changes in PEEP. This study aimed to investigate the association between changes in shunt, low and high ventilation/perfusion ...
D. Karbing, M. Panigada, N. Bottino, E. Spinelli, A. Protti, S. Rees, L. Gattinoni   +6 more
semanticscholar   +1 more source

Ventilation-induced acute kidney injury in acute respiratory failure: Do PEEP levels matter?

Critical Care
Acute Respiratory Distress Syndrome (ARDS) is a leading cause of morbidity and mortality among critically ill patients, and mechanical ventilation (MV) plays a critical role in its management.
Martín H. Benites, F. Suárez-Sipmann, E. Kattan, Pablo Cruces, Jaime Retamal   +4 more
semanticscholar   +1 more source

PEEP in the pandemic: supporting parent learning on-line [PDF]

, 2020
- A research project entitled 'Evaluating parent and practitioner views of participation in the PEEP Learning Together Programme and developing an enhanced delivery model' is ongoing.
MacKenzie, Muriel, McCartney, Elspeth, Rogerson, Joanna, Hale, Hannah   +3 more
core  

Intraoperative Driving Pressure-Guided High PEEP vs Standard Low PEEP for Postoperative Pulmonary Complications.

Journal of the American Medical Association (JAMA)
Importance The effect of individualized high positive end-expiratory pressure (PEEP) and recruitment maneuvers, targeting a low driving pressure, on clinical outcomes in patients undergoing open abdominal surgery is uncertain.
G. Dorland, Marcelo Gama de Abreu, S. Hemmes, L. Hol, M. W. Hollmann, D. V. van Meenen, S. Nijbroek, M. Schultz, A. Serpa, T. D. Vermeulen   +9 more
semanticscholar   +1 more source

Positive end-expiratory pressure titration in COVID-19 acute respiratory failure: electrical impedance tomography vs. PEEP/FiO2 tables

Critical Care, 2020
To the Editor, Hypoxemic acute respiratory failure (hARF) secondary to COVID-19 presents with heterogeneous features depending on several determinants, such as the extent of intravascular microthrombosis, superinfections, and other complications [1, 2 ...
Nicolò Sella, F. Zarantonello, G. Andreatta, Veronica Gagliardi, A. Boscolo, P. Navalesi   +5 more
semanticscholar   +1 more source