Results 81 to 90 of about 87,983,909 (290)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Efficient and Effective Use of Peer Teaching for Medical Student Simulation

Western Journal of Emergency Medicine, 2017
Simulation is increasingly used in medical education, promoting active learning and retention; however, increasing use also requires considerable instructor resources.
House, Joseph, Choe, Carol H, Wourman, Heather L, Berg, Kristin M, Fischer, Jonathan P, Santen, Sally A   +5 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Being a Peer Mentor

Whether you are new to mentoring or looking to refine your skills, this guide will cover the essentials of effective communication, why peer support matters, and how you can build inclusive and meaningful relationships with the students you ...
Peer Mentoring team
core   +1 more source

Peer-Assisted Information-Centric Network (PICN): A Backward Compatible Solution

IEEE Access, 2017
Information-centric networking (ICN) is a promising solution for most of Internet applications where the content represents the core of the application.
Zeinab Zali, Ehsan Aslanian, Mohammad Hossein Manshaei, Massoud Reza Hashemi, Thierry Turletti   +4 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

The Role of Technical Car Features in Managing and Promoting New Peer-to-Peer Car-Sharing Systems: Insights from Potential Users and Strategic Implications for Service Providers

Applied Sciences
Peer-to-peer car-sharing systems are an evolving branch of urban mobility, aligning with global trends focused on sustainable development and reducing congestion in cities.
Katarzyna Turoń, Andrzej Kubik, Piotr Folęga, Andrzej Wilk, Peter Bindzar, Truong M. N. Bui   +5 more
doaj   +1 more source

Peer-to-Peer Semantic Wikis [PDF]

, 2009
This paper presents SWOOKI the first peer-to-peer semantic wiki. A P2P semantic wiki combines advantages of both semantic wikis and P2P Wikis. A P2P semantic wiki network is composed of a set of interconnected autonomous servers that can dynamically join and leave the network.
Skaf, Hala, Rahhal, Charbel, Molli, Pascal   +2 more
openaire   +4 more sources

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source