Results 101 to 110 of about 181,200 (325)

PEER: Exploring the Lives of Sex Workers in Tyne and Wear [PDF]

open access: yes, 2013
The overall aim of the PEER project is to provide a robust evidence base regarding the experiences andservice needs of women engaging in sex work in Tyne and Wear, in order to inform local knowledge, policyand practice in this area.
Irving, Adele, Laing, Mary
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Reconsidering Public Relations’ Infatuation with Dialogue: Why Engagement and Reconciliation Can Be More Ethical Than Symmetry and Reciprocity [PDF]

open access: yes, 2006
Advocates of dialogic communication have promoted two-way symmetrical communication as the most effective and ethical model for public relations. This article uses John Durham Peters’s critique of dialogic communication to reconsider this infatuation ...
Berg, Kati Tusinski, Stoker, Kevin L.
core   +1 more source

Optimising the learning of gifted aboriginal students [PDF]

open access: yes, 2006
[Abstract]: According to the United Nations Educational, Scientific and Cultural Organisation's (2000) 'Education for All' goals, all students are entitled to opportunities to fulfil their potential.
Garvis, Susanne
core   +2 more sources

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

“Sharing” tourism as an opportunity for territorial regeneration: the case of Iseo Lake, Italy

open access: yesHungarian Geographical Bulletin, 2019
The spread of sharing economics platforms in the world of travels has highlighted the little known phenomenon of the rental of houses and apartments with a non-enterprise management.
Sara Belotti
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Guidelines for peer observation of learning and teaching [PDF]

open access: yes, 2000
These guidelines have been prepared as a starting point for schools of education or education departments wishing to undertake peer observation of learning and teaching, particularly as preparation for a Subject Review.
Gosling, David
core  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

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