Results 91 to 100 of about 1,542,515 (311)

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Multiple attachment perspectives: the relationship between interpersonal attachment from family and school environments and children’s learning engagement

open access: yesBMC Psychology
Objectives Abundant evidence has demonstrated that positive interpersonal relationships promote children’s learning engagement. However, most existing studies only focus on the role of one or two attachment relationships, and few studies examine the ...
Qi Li, Die Wang, Guihua Qin
doaj   +1 more source

Relationship between parents, peer, lecturer attachment and Islamic resiliency among University Putra Malaysia students [PDF]

open access: yes, 2016
The main purpose of this study is to determine the relationship between parents,peer, lecturer attachment and resiliency among UPM students. Three factors which are parents, peer and lecturer attachment have been studied about their relationship with ...
Hamsan, Hanina Halimatusaadiah
core  

Attachment-related attention bias plays a causal role in trust in maternal support [PDF]

open access: yes, 2019
The current study was designed to test whether children's ability to flexibly shift their attention (from their mother during distress to peers during exploration and vice versa) causally increases children's trust in the mother's support.
Bosmans, Guy   +3 more
core   +2 more sources

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Preferential survival in models of complex ad hoc networks

open access: yes, 2007
There has been a rich interplay in recent years between (i) empirical investigations of real world dynamic networks, (ii) analytical modeling of the microscopic mechanisms that drive the emergence of such networks, and (iii) harnessing of these ...
Adamic   +34 more
core   +1 more source

An adaptation of the experiences in close relationships scale-revised for use with children and adolescents [PDF]

open access: yes, 2011
The investigation of attachment processes during middle childhood and early adolescence has been hampered by a relative lack of measures for this age group differentiating between two fundamental attachment dimensions, that is, anxiety and avoidance. The
bosmans, Guy   +3 more
core   +2 more sources

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

open access: yesFEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde   +3 more
wiley   +1 more source

Efficiency of attack strategies on complex model and real-world networks

open access: yes, 2013
We investigated the efficiency of attack strategies to network nodes when targeting several complex model and real-world networks. We tested 5 attack strategies, 3 of which were introduced in this work for the first time, to attack 3 model (Erdos and ...
Bellingeri, Michele   +2 more
core   +1 more source

Why are undergraduate emerging adults anxious and avoidant in their romantic relationships? The role of family relationships [PDF]

open access: yes, 2019
The exploration of and search for romantic relationships is one of the developmental tasks that characterise emerging adulthood, a new developmental phase halfway between adolescence and full adulthood.
Díez López, Marta   +2 more
core   +1 more source

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