Results 81 to 90 of about 530,627 (295)

Analisis Keterampilan Proses Sains Menggunakan Peer Assessment Pada Pembelajaran Inkuiri Terbimbing Dan Direct Instruction [PDF]

, 2013
This study aims to know: (1) difference KPS assessed by student through peer assessment and teacher on guided inquiry learning; (2) difference KPS assessed by student through peer assessment and teacher on direct instruction; (3) interaction between ...
Maharta, N. (Nengah), Mulyasari, F. (Fera), Rosidin, U. (Undang)   +2 more
core  

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

PERBANDINGAN PENGARUH MODEL PEMBELAJARAN KOOPERATIF DAN PEER TEACHING TERHADAP HASIL BELAJAR KETERAMPILAN LOB BERTAHAN DAN KETERAMPILAN SOSIAL [PDF]

, 2014
Tujuan penelitian ini untuk menguji perbedaan pengaruh model pembelajaran kooperatif dengan peer teaching terhadap hasil belajar keterampilan dasar lob bertahan dan keterampilan sosial di SMA Negeri 1 Bale Endah.
Safitri, Neneng Aldila
core  

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Enhancing Science Competence: Evaluating the Effects of Peer Instruction and Conceptual Questions on Theoretical, Axiological, and Applied Knowledge in Physics Education [PDF]

Educaţia 21
This study evaluates the impact of the Peer Instruction method combined with Conceptual Questions on students’ science competence in physics. The research focused on three components of science competence: theoretical knowledge, axiological knowledge ...
Mihail Calalb, Viorel Dabija
doaj   +1 more source

PERBANDINGAN PENGARUH MODEL PEMBELAJARAN KOOPERATIF DAN PEER TEACHING TERHADAP HASIL BELAJAR KETERAMPILAN LOB BERTAHAN DAN KETERAMPILAN SOSIAL: Study Eksperimen Terhadap Siswa SMA N 1 Baleendah [PDF]

, 2014
Tujuan penelitian ini untuk menguji perbedaan pengaruh model pembelajaran kooperatif dengan peer teaching terhadap hasil belajar keterampilan dasar lob bertahan dan keterampilan sosial di SMA Negeri 1 Bale Endah.
Safitri, neneng Aldila
core  

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

10 Key Policies and Practices for Teaching English Language Learners [PDF]

, 2018
The ninth installment of MCPER's "10 Key" series, this document distills the latest research findings into 10 easy-to-follow recommendations that states, school districts, and schools can use to improve instruction for English language learners.
The Meadows Center for Preventing Educational Risk
core   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source