Results 111 to 120 of about 15,798,848 (319)

Theory of mind skills and peer relationships in children’s adjustment to preschool

open access: yesFrontiers in Psychology
School adjustment affects children’s future lives in many ways. This study examined the relationship between ToM skills, peer relationships, and school adjustment.
Esra Ünlüer
doaj   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

Conflicts in the classroom: contributions from a study on emotional self-regulation

open access: yesFrontiers in Education
To support teacher-guided techniques that support emotional self-regulation, this study characterizes how conflicts that arise in the classroom are identified and resolved.
Marina Alarcón-Espinoza   +2 more
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

PEER Summary - Points of agreement and key findings

open access: yes, 2012
The PEER Executive Project Partners stress the points of agreement and key findings from the commissioned research in this ...
Armbruster, Chris
core   +2 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Friendship in Preschoolers and Younger Schoolchildren: a Review of Diagnostic Tools

open access: yesНациональный психологический журнал
Background. Friendship plays an important role in children’s socio-emotional development. However, research on the characteristics of friendship as well as its associations with various aspects of development and well-being in preschool and early school ...
Yuriy P. Zinchenko   +3 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

When Open Hypermedia Meets Peer-to-Peer Computing

open access: yes, 2004
We describe the extension to our previous work on a Web-based peer-to-peer open hypermedia system, the DDLS. We enrich the peer model by introducing query history, and propose the use of the naive estimator which utilises the local knowledge of peers to ...
De Roure, David, Hall, Wendy, Zhou, Jing
core   +2 more sources

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