Results 51 to 60 of about 482,120 (304)

The Effect of Islamic Value-Based Parenting and Peer Relationships on Adolescents' Prosocial Behavior in the Digital Era

Psikis: Jurnal Psikologi Islami
Rapid technological developments have pushed adolescents towards individualism and eroded their concern for the environment, thus emphasizing the importance of parenting patterns based on Islamic values ​​to form a caring and responsible prosocial ...
Layyinah Layyinah, Neneng Tati Sumiati, Sri Hidayati, Syadza Syadza, Gusty Syaiim Framita   +4 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Perceptions and correlates of peer-victimization and bullying

, 2007
The experiences of peer-victimization and bullying are often treated empirically as though they are conceptually indistinct. Both involve repeated aggression,but definitions of bullying additionally emphasize the importance of aggressor intent and ...
Warden, David, Boyle, James, Boyle, James M. E., Hunter, Simon C.; id_orcid, Hunter, Simon C.   +4 more
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Determinants of peer selection for collaborative group work of third-year bachelor students in a medical degree programme with learning communities

Medical Education Online, 2022
The social capital theory reveals the importance of peer relationships on students’ learning. However, it is unclear how students select their collaborators under the influence of their previous collaborations and backgrounds. This study explores to what
Yan Zhou, Jasperina Brouwer, Nicolaas Adrianus Bos, Agnes D. Diemers   +3 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Peer Conformity Affects Smoking Behavior among Male Adolescents in a High School in Padang, Indonesia

Nurse Media: Journal of Nursing, 2020
Background: Peers contribute to the development of adolescents’ behavior during the transition period. Adolescents often justify their behavior with peers to confirm social norms of their surroundings.
Mahathir Mahathir, Prilya Vitamaharanie, Hermalinda Hermalinda   +2 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source