Results 91 to 100 of about 1,447,355 (302)
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
The Next 50 Years: Considering Gender as a Context for Understanding Young Children’s Peer Relationships [PDF]
, 2004 The study of children’s peer relationships has been well represented within the pages of Merrill-Palmer Quarterly. Particularly over the last decade, the pace of publishing studies on peer relationships has increased.
Fabes, Richard A. +2 more
core +1 more source
Structure of Peer-to-Peer Social Networks [PDF]
, 2006 This paper presents a statistical analysis of the structure of Peer-to-Peer (P2P) social networks that captures social associations of distributed peers in resource sharing.
Fang Wang +3 more
core +2 more sources
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Behavioral SciencesThis study used latent transition analysis to explore the categories of self-concept clarity transformation and their influencing factors among adolescents.
Yang Yang +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Loneliness in adolescence: prevalence, developmental contexts, and interventions
Frontiers in PsychiatryLoneliness, though often mistaken for social isolation, is a distinct experience that affects individuals across the lifespan and is especially salient during adolescence.
Lily Verity +2 more
doaj +1 more source
Self-organizing peer-to-peer social networks [PDF]
, 2008 This is the author's accepted manuscript. The final published article is available from the link below. Copyright @ 2008 The Authors.Peer-to-peer (P2P) systems provide a new solution to distributed information and resource sharing because of its ...
Sun, Y, Wang, F
core +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Pedagogía Social: Revista Interuniversitaria, 2008 Este artículo se centra en los comportamientos que adopta el alumnado espectador de situaciones de bulling con sus iguales. La profundización en las causas de la escasa intervención de los espectadores en estas situaciones está siendo objeto de interés ...
Carmen Carmen Orte Socias
doaj +1 more source