Results 241 to 250 of about 339,887 (309)

A Drug‐Gated, Modular STAb‐T Immunotherapy With External Control

Advanced Science, EarlyView.
Engineered STAb‐TON cells act as programmable living factories that continuously secrete inactive antibody modules, which assemble extracellularly into a functional T cell engager only upon small‐molecule administration. This externally controlled platform enables reversible, on‐demand regulation of antitumor immunity, establishing a new paradigm for ...
Susana Luengo‐Arias, Carmen Domínguez‐Alonso, Ivana Zagorac, Antonio Tapia‐Galisteo, Eva García‐Veros, Laura Rubio‐Pérez, Marina Gómez‐Rosel, Patricia Fuentes, Patricia Hernández‐López, Óscar Aguilar‐Sopeña, Laura Almagro‐Puente, Sonia Martínez‐González, Lucía Cañizares‐Moscato, María Rivas‐Sánchez, Belén Blanco, Ángel Ramírez‐Fernández, Laura Díez‐Alonso, Carmen Blanco‐Aparicio, Javier Arroyo‐Ródenas, Jorge Martínez‐Torrecuadrada, María L. Toribio, Pedro Roda‐Navarro, Anaïs Jiménez‐Reinoso, Luis Álvarez‐Vallina   +23 more
wiley   +1 more source

A Biofabricated Human Acinus‐on‐a‐Chip Unveils Mechanotransductive Drivers of Ventilator‐Induced Lung Injury via Decoupling Volutrauma and Barotrauma

Advanced Science, EarlyView.
This bioinspired acinus‐on‐a‐chip recapitulates VILI pathology, revealing that volutrauma drives P53/NF‐κB pathways while barotrauma triggers mitochondrial‐Wnt dysregulation. A fibrotic transitional cell cluster was identified. Pharmacological interventions targeting these pathways significantly ameliorated injury, establishing a mechanobiological ...
Heng Lu, Liansheng Liu, Zengyong Hu, Shuxian Fang, Ruohan Ren, Sidi Liu, Meng Zhao, Zhiting Luo, Ziyue Zhang, Wenlong Shao, Qian Liu   +10 more
wiley   +1 more source

Profile and Predictors of Hepatitis B Surface Antigen Seroreversion Following PEG-IFNα with or Without Therapeutic Vaccine BRII-179 or siRNA Elebsiran: A Post Hoc Pooled Analysis of Two Randomized Controlled Trials in Patients with Chronic Hepatitis B Virus Infection. [PDF]

Vaccines (Basel)
Gao Z, Lin B, Wong GL, Yuen MF, Liu Y, Zhu C, Cao K, Tian A, Chen X, Zhu Q, Margolis D, Jia J, Hong Z.   +12 more
europepmc   +1 more source

Reduced lumbar myofascial mobility in chronic low back pain quantified using MR elastography-based slip interface imaging. [PDF]

Eur Radiol Exp
Hojo E, Ito D, Sui Y, Shan X, Rossman P, Manduca A, Powell GM, An KN, Ehman RL, Nanda S, Bauer BA, Yin Z.   +11 more
europepmc   +1 more source

Prevalence of Decisional Regret and Associated Risk Factors in Patients With Hepatitis B Undergoing Pegylated Interferon Alpha Therapy. [PDF]

Gastroenterol Res Pract
Lin Y, Xiong H, Yi S, Xie S.
europepmc   +1 more source

Fluorescent Biofunctionalized Silver and Gold Nanoparticles: Bright Tools for Bioimaging Applications. [PDF]

ACS Omega
Olivieri E, Bertelà F, Lemaire S, Parisi M, Battistini L, Borsellino G, Angelini DF, Beyer E, Wolanin B, Sobol T, Maraloiu VA, Iucci G, Battocchio C, Venditti I.   +13 more
europepmc   +1 more source

Melt Electrospinning of Poly(ε-caprolactone)/Poly(ethylene oxide)/Poly(ethylene glycol) Blend: Effects on Structure and Cellular Compatibility. [PDF]

ACS Omega
Karimi E, Garakani MM, Heuzey MC, Mighri F, Rosenzweig DH, Ajji A.   +5 more
europepmc   +1 more source

Long-Acting PEG-rhGH in Short Children Born SGA in China: 4-Year Results from a Randomized Phase 2 Study.

Horm Res Paediatr
Hou L, Luo X, Chen X, Du H, Yang Y, Luo FH, Chen Y, Ma D, Xiang W, Zhu X.   +9 more
europepmc   +1 more source

Accelerating polycaprolactone degradation through bottlebrush architecture.

Polym Chem
Garcia J, Anikin MM, Maryasevskaya AV, Piryazev AA, Umarov AZ, Wang Z, Dobrynin AV, Ivanov DA, Sheiko SS.   +8 more
europepmc   +1 more source