Results 141 to 150 of about 6,229,738 (373)

Dual-targeted polyplexes based on sequence-defined peptide-PEG-oligoamino amides.

open access: yesJournal of Pharmacy and Science, 2015
For active cell targeting, viruses frequently capitalize on dual-receptor binding. With the intention to mimic this natural process, a dual peptide-based approach for targeting cancer cells was evaluated.
P. Kos   +5 more
semanticscholar   +1 more source

Controlled Release of Human Dental Pulp Stem Cell‐Derived Exosomes from Hydrogels Attenuates Temporomandibular Joint Osteoarthritis

open access: yesAdvanced Healthcare Materials, EarlyView.
Exosomes can reduce tissue damage in temporomandibular joint osteoarthritis (TMJOA), but rapid clearance limits their efficacy. This study encapsulates exosomes in hyaluronic acid hydrogels for controlled release. In a rat model, hydrogel‐encapsulated exosomes outperform free exosomes in preserving bone integrity and reducing tissue destruction ...
Victor Diez‐Guardia   +7 more
wiley   +1 more source

The investigation of polymer-siRNA nanoparticle for gene therapy of gastric cancer in vitro

open access: yesInternational Journal of Nanomedicine, 2010
Ying Wu1, Weiwei Wang2, Yinting Chen1, Kaihong Huang1, Xintao Shuai2, Qikui Chen1, Xuexian Li1, Guoda Lian11Department of Gastroenterology, The Second Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China; 2BME Center, School of Chemistry and ...
Ying Wu   +3 more
doaj  

High performance shape memory polyurethane synthesized with high molecular weight polyol as the soft segment [PDF]

open access: yes, 2012
Shape memory polyurethanes (SMPUs) are typically synthesized using polyols of low molecular weight (MW~2,000 g/mol) as it is believed that the high density of cross-links in these low molecular weight polyols are essential for high mechanical strength ...
Ahmad, Manzoor   +6 more
core   +2 more sources

“Therapies Through Gut:” Targeted Drug Delivery for Non‐Gastrointestinal Diseases by Oral Administration

open access: yesAdvanced Healthcare Materials, EarlyView.
Schematic illustration of the mechanism of targeted delivery of nanoparticles including 1) paracellular, 2) endolysosomal escape, 3) receptor mediated endocytosis, and 4) M cell mediated transport for non‐GI diseases by oral administration such as atherosclerosis, cancer, diabetes, and brain diseases. Abstract Oral drug delivery is a promising approach
Subarna Ray   +2 more
wiley   +1 more source

What’s Wrong with PEG? [PDF]

open access: yes, 2015
PEG is a newer investment ratio measure of a security’s PE ratio divided by the firm’s growth rate as a percentage. It is examined and contrasted with other investment valuation measures.
Higgins, Charles J.
core   +1 more source

Monodispersed DOTA-PEG–Conjugated Anti-TAG-72 Diabody Has Low Kidney Uptake and High Tumor-to-Blood Ratios Resulting in Improved64Cu PET [PDF]

open access: bronze, 2010
Lin Li   +14 more
openalex   +1 more source

The influence of Gd-DOTA conjugating ratios to PLGA-PEG micelles encapsulated IR-1061 on bimodal over-1000 nm near-infrared fluorescence and magnetic resonance imaging

open access: hybrid, 2022
Doan Thi Kim Dung   +8 more
openalex   +2 more sources

Supercritical Fluid‐Processed Multifunctional Hybrid Decellularized Extracellular Matrix with Chitosan Hydrogel for Improving Photoaged Dermis Microenvironment

open access: yesAdvanced Healthcare Materials, EarlyView.
These findings advance tissue repair by offering a multifunctional filler that improves large‐scale volume retention, elasticity, and support for vascularized tissue growth. The decellularized extracellular matrix (dECM)‐based material provides low injection force and minimizes swelling, ensuring sustained volume. Combining CMC with supercritical fluid‐
Seol‐Ha Jeong   +6 more
wiley   +1 more source

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