Functional Polarization of Liver Macrophages by Glyco Gold Nanoparticles
Macrophages play a critical role in several pathophysiological diseases by being involved in the activation of adaptive and innate immune responses. The repolarization of macrophages using gold nanoparticles functionalized with glycans for a more selective targeting toward a restorative phenotype leads to an amelioration of the events.
Jennifer Fernandez Alarcon+25 more
wiley +1 more source
Preparation of Wood Fiber-Polyurethane Plastic Composite with Water Resistance and High Strength. [PDF]
Yuan X, Fu S, Liu H.
europepmc +1 more source
This study presents a novel approach for treating Duchenne muscular dystrophy using mRNA encoding PGC‐1α4. Nanomicelle‐delivered Pgc‐1α4 mRNA enhances muscle damage resistance and mitochondrial activity in dystrophic muscles. This study demonstrates the potential of mRNA therapy for neuromuscular diseases like Duchenne muscular dystrophy and highlights
Xuan Du+7 more
wiley +1 more source
Cartilage-bioinspired tenacious concrete-like hydrogel verified via in-situ testing. [PDF]
Liu J, Zhao W, Ma Z, Zhao H, Ren L.
europepmc +1 more source
Nanotherapy for Neural Retinal Regeneration
Nanotechnology enhances ophthalmic treatments by improving drug delivery and regenerating ocular tissues, combating vision loss from retinal diseases through innovative nano‐systems. This review outlines ocular anatomy, pathology, immune microenvironment, and barriers, detailing nanocarrier characteristics, classification, and preparation methods, and ...
Chuyao Yu+11 more
wiley +1 more source
Enhanced brightness and photostability of dye-sensitized Nd-doped rare earth nanocomposite for in vivo NIR-IIb vascular and orthotopic tumor imaging. [PDF]
Lin SL+7 more
europepmc +1 more source
Advances in Symbiotic Bioabsorbable Devices
This review focuses on recent advances in bioabsorbable devices. This review concludes innovation at the material, device, and system levels, the significant advances toward biomedical applications. This review discusses and highlights the challenges and trends in symbiotic bioresorbable electronics, and provides a new direction for the development of ...
Chang Zhu+3 more
wiley +1 more source
Three-Dimensional Polyglycerol-PEG-Based Hydrogels as a Universal High-Sensitivity Platform for SPR Analysis. [PDF]
Krage C+12 more
europepmc +1 more source
NF2 is Essential for Human Endoderm Development
This study demonstrates that NF2, moesin‐ezrin‐radixin like (MERLIN) tumor suppressor (NF2) is essential for human endoderm formation. NF2 knockout human induced pluripotent stem cells fail to form endoderm both in vitro and in vivo due to yes‐associated protein 1 (YAP1) nuclear translocation, redirecting differentiation toward myofibroblast‐like cells.
Minjin Jeong+5 more
wiley +1 more source
Colostrum-Derived Melatonin Plus PEG Microspheres Modulate the Oxidative Metabolism of Human Colostrum Phagocytes. [PDF]
Silva CG+7 more
europepmc +1 more source