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Preparation and optimization of biodegradable self-assembled PCL-PEG-PCL nano-sized micelles for drug delivery systems

, 2020
Biodegradable polymeric micelles have potential therapeutic applications; nevertheless, preparing micelles of a specific diameter and uniform size distribution is a challenge.
Özlem Gökçe Kocabay, O. Ismail
semanticscholar   +1 more source

PEG-based nanocomposite hydrogel: Thermo-responsive sol-gel transition and degradation behavior controlled by the LA/GA ratio of PLGA-PEG-PLGA

Polymer Degradation and Stability, 2018
Abstract The sol-gel transition behavior and the degradation behavior of the nanocomposites consisting of laponite clay nanoparticles and poly( d,l -lactide-co-glycolide)-b-poly(ethylene glycol)-b-poly( d,l -lactide-co-glycolide) (PLGA-PEG-PLGA) triblock copolymers (laponite/PLGA-PEG-PLGA nanocomposites) were studied changing the LA/GA ratios of the ...
Midori Kitagawa   +2 more
openaire   +1 more source

Preparation and Characterization of PLA-PEG-PLA/PEI/DNA Nanoparticles for Improvement of Transfection Efficiency and Controlled Release of DNA in Gene Delivery Systems

Iranian journal of pharmaceutical research, 2019
Tri-block poly (lactide) poly(ethylene glycol) poly(lactide) (PLA–PEG–PLA) copolymers are among the most attractive nano-carriers for gene delivery into mammalian cells, due to their biocompatibility and biodegradability properties.
A. Amani   +3 more
semanticscholar   +1 more source

Development of CdS nanorods of high aspect ratio under hydrothermal conditions with PEG template

Journal of Crystal Growth, 2011
Abstract Cadmium sulfide (CdS) one dimensional (1D) nanocrystals were prepared using a polyethylene glycol (PEG) assisted hydrothermal synthesis. X-ray diffraction result confirms that the nanorods are of hexagonal structure and the selected area electron diffraction (SAED) identifies the single crystalline nature of the sample.
N.S. Nirmala Jothi   +4 more
openaire   +1 more source

Thermal and rheological behavior of PEG-based nanocomposites: Effect of filler aspect ratio and size

AIP Conference Proceedings, 2018
In this work, polyethylene glycol (PEG) nanocomposites containing different nanofillers (namely boehmites and hydrotalcites) were prepared through melt compounding and their thermal and rheological behavior was thoroughly investigated. The obtained results showed that the two types of nanofillers interact in a different way with the polymer matrix ...
Rossella Arrigo   +2 more
openaire   +2 more sources

Characteristics and cytotoxicity of folate-modified curcumin-loaded PLA-PEG micellar nano systems with various PLA:PEG ratios

International Journal of Pharmaceutics, 2016
Targeting delivery system use natural drugs for tumor cells is an appealing platform help to reduce the side effects and enhance the therapeutic effects of the drug. In this study, we synthesized curcumin (Cur) loaded (D, L Poly lactic - Poly ethylenglycol) micelle (Cur/PLA-PEG) with the ratio of PLA/PEG of 3:1 2:1 1:1 1:2 and 1:3 (w/w) and another ...
Quoc Thong, Phan   +5 more
openaire   +2 more sources

Optimization of Weight Ratio for DSPE-PEG/TPGS Hybrid Micelles to Improve Drug Retention and Tumor Penetration

Pharmaceutical Research, 2018
To enhance therapeutic efficacy and prevent phlebitis caused by Asulacrine (ASL) precipitation post intravenous injection, ASL-loaded hybrid micelles with size below 40 nm were developed to improve drug retention and tumor penetration.ASL-micelles were prepared using different weight ratios of 1,2-distearoyl-sn-glycero-3-phosphoethanolamine ...
Jin, Ya   +7 more
openaire   +3 more sources

Is PEG Ratio a Better Tool for Valuing the Companies as Compared to P/E Ratio? (A Case Study on Selected Automobile Companies)

International Journal of Banking, Risk and Insurance, 2015
The securities in the capital markets can be analyzed with the help of Fundamental Analysis or Technical Analysis or both. As for many small investors, technical analysis is a complex tool to be used for analyzing the securities, they basically use fundamental analysis in formulating their effective investment strategies.
Bharat Kumar Meher, Saurabh Sharma
openaire   +1 more source

Contact Force/Torque Prediction and Analysis Model for Large Length-diameter Ratio Peg-in-hole Assembly

2018 IEEE International Conference on Robotics and Biomimetics (ROBIO), 2018
Large length-diameter ratio peg-in-hole assembly is a hard and significant issue in modern industry. The prediction and control of the contact force/torque play a crucial part in flexible assembly. They ensure that the contact force/torque data are within limits in assembly process, which can prevent jam and protect devices. In this paper, we propose a
Yuchen Wang   +7 more
openaire   +1 more source

Single Force-Guided Precision Peg-in-Hole Search of Cylindrical Part with Small Length/Diameter Ratio

2018 IEEE 8th Annual International Conference on CYBER Technology in Automation, Control, and Intelligent Systems (CYBER), 2018
This paper presents an approach to deal with precise positioning for valve spool of precision solenoid valve in automatic assembly. The valve spool is the cylindrical part with length/diameter ratio less than 0.3 and the mating clearance is narrower. At present, its assembly process is positioning first and then inserting.
Bin Zhou   +3 more
openaire   +1 more source

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