Results 321 to 330 of about 7,450,425 (377)

Tailoring the adjuvanticity of lipid nanoparticles by PEG lipid ratio and phospholipid modifications

Nature Nanotechnology
Lipid nanoparticles (LNPs) represent the leading delivery platform for mRNA vaccines with advantageous biocompatibility, scalability, adjuvant activity and often an acceptable safety profile. Here we investigate the physicochemical characteristics and adjuvanticity of four-component LNPs.
Máté Vadovics, Wenchen Zhao, Emily F. Daley, Kieu Lam, Owen Daly, Khalid Rashid, Hailey R. Lee, Petra Schreiner, Kendall A. Lundgreen, Brian T. Gaudette, Vladimir V. Shuvaev, Evguenia Arguiri, Hiromi Muramatsu, András Sárközy, Thandiswa Mdluli, Junchao Xu, Xuexiang Han, Nina De Luna, Diana Castaño, Emily Bettini, Edit Ábrahám, Zoltan Lipinszki, Giuseppe Carlucci, Avinash Haridas Bansode, Katelyn Nguyen, Thuc M. Le, Tony Luu, Vladimir R. Muzykantov, Paul Bates, David Allman, Michael J. Mitchell, Michela Locci, Caius G. Radu, James Heyes, Norbert Pardi   +34 more
openaire   +2 more sources

Is PEG Ratio a Better Tool for Valuing the Companies as Compared to P/E Ratio? (A Case Study on Selected Automobile Companies)

International Journal of Banking, Risk and Insurance, 2015
The securities in the capital markets can be analyzed with the help of Fundamental Analysis or Technical Analysis or both. As for many small investors, technical analysis is a complex tool to be used for analyzing the securities, they basically use fundamental analysis in formulating their effective investment strategies.
Bharat Kumar Meher, Saurabh Sharma
openaire   +1 more source

Preparation and Characterization of PLA-PEG-PLA/PEI/DNA Nanoparticles for Improvement of Transfection Efficiency and Controlled Release of DNA in Gene Delivery Systems

Iranian journal of pharmaceutical research, 2019
Tri-block poly (lactide) poly(ethylene glycol) poly(lactide) (PLA–PEG–PLA) copolymers are among the most attractive nano-carriers for gene delivery into mammalian cells, due to their biocompatibility and biodegradability properties.
A. Amani, Toraj Kabiri, Samira Shafiee, A. Hamidi   +3 more
semanticscholar   +1 more source

Development of CdS nanorods of high aspect ratio under hydrothermal conditions with PEG template

Journal of Crystal Growth, 2011
Abstract Cadmium sulfide (CdS) one dimensional (1D) nanocrystals were prepared using a polyethylene glycol (PEG) assisted hydrothermal synthesis. X-ray diffraction result confirms that the nanorods are of hexagonal structure and the selected area electron diffraction (SAED) identifies the single crystalline nature of the sample.
N.S. Nirmala Jothi, P. Dennis Christy, A.R. Baby Suganthi, G. Ramalingam, P. Sagayaraj   +4 more
openaire   +1 more source

Thermal and rheological behavior of PEG-based nanocomposites: Effect of filler aspect ratio and size

AIP Conference Proceedings, 2018
In this work, polyethylene glycol (PEG) nanocomposites containing different nanofillers (namely boehmites and hydrotalcites) were prepared through melt compounding and their thermal and rheological behavior was thoroughly investigated. The obtained results showed that the two types of nanofillers interact in a different way with the polymer matrix ...
Rossella Arrigo, Laura Montanaro, Giulio Malucelli   +2 more
openaire   +2 more sources

Tuning the in vivo transfection efficiency of mRNA-Loaded lipoplexes by PEG-Lipid structure and ratio

European Journal of Pharmaceutics and Biopharmaceutics
The development of mRNA-based antiviral and antitumor therapeutics is progressing rapidly and shows considerable promise. Optimizing the composition of liposomal delivery vehicles is critical for enhancing mRNA vaccine efficacy. Among their components, PEG-lipids require careful optimization to improve the colloidal stability of mRNA-liposome complexes,
O V, Markov, D N, Antropov, E V, Shmendel, P A, Puchkov, O A, Yakovlev, M D, Kerbitskaya, E S, Zhuravlev, A S, Dome, E P, Goncharova, D N, Shcherbakov, M A, Zenkova, M A, Maslov, G A, Stepanov   +12 more
openaire   +2 more sources

Optimization of Weight Ratio for DSPE-PEG/TPGS Hybrid Micelles to Improve Drug Retention and Tumor Penetration

Pharmaceutical Research, 2018
To enhance therapeutic efficacy and prevent phlebitis caused by Asulacrine (ASL) precipitation post intravenous injection, ASL-loaded hybrid micelles with size below 40 nm were developed to improve drug retention and tumor penetration.ASL-micelles were prepared using different weight ratios of 1,2-distearoyl-sn-glycero-3-phosphoethanolamine ...
Jin, Ya, Wu, Zimei, Li, Caibin, Zhou, Weisai, Shaw, John, Baguley, Bruce, Liu, Jianping, Zhang, Wenli   +7 more
openaire   +3 more sources

Contact Force/Torque Prediction and Analysis Model for Large Length-diameter Ratio Peg-in-hole Assembly

2018 IEEE International Conference on Robotics and Biomimetics (ROBIO), 2018
Large length-diameter ratio peg-in-hole assembly is a hard and significant issue in modern industry. The prediction and control of the contact force/torque play a crucial part in flexible assembly. They ensure that the contact force/torque data are within limits in assembly process, which can prevent jam and protect devices. In this paper, we propose a
Yuchen Wang, Peng Wang 0024, Changchun Liu, Gaoming Hao, Zhao Xiong, Xusong Quan, Xiaodong Yuan, Hai Zhou   +7 more
openaire   +1 more source

Synthesis and Tailoring Morphological and Optical Characteristics of PMMA/PEG/Si3N4 Hybrid Nanomaterials for Optics and Quantum Nanoelectronics Applications

Silicon, 2023
Ghaith Ahmed, A. Hashim
semanticscholar   +1 more source

Dual surface modification with PEG and corn trypsin inhibitor: Effect of PEG:CTI ratio on protein resistance and anticoagulant properties

Journal of Biomedical Materials Research Part A, 2012
AbstractThe objective of this study was to investigate the bioactivity and protein‐resistant properties of dual functioning surfaces modified with PEG for protein resistance and corn trypsin inhibitor (CTI) for anticoagulant effect. Surfaces on gold substrate were prepared with varying ratios of free PEG to CTI‐conjugated PEG.
Sara, Alibeik, Shiping, Zhu, Jonathan W, Yau, Jeffrey I, Weitz, John L, Brash   +4 more
openaire   +2 more sources