Results 111 to 120 of about 373,225 (307)

Detaching Photosensitive Nanoparticles from Cells Prevents Them from Remaining in Cells after Photoporation. [PDF]

Adv Sci (Weinh)
Phenylboronic acid‐functionalized gold nanoparticles reversibly attach to cell‐surface glycans, enhancing photoporation‐mediated intracellular delivery. After irradiation, ATP competitively disrupts the boronic ester interactions and removes cell‐associated nanoparticles, markedly reducing residual gold.
Lu T, Nikolić M, Huang B, Punj D, De Keersmaecker H, Van Acker T, Xie W, Vanlauwe F, Blondeel P, De Graeve L, Sauvage F, Xiong R, Huang C, Vanhaecke F, Braeckmans K, De Smedt SC.   +15 more
europepmc   +2 more sources

Bioinspired Porphyrin‐Based Catalysts From Temporospatial Confined Frameworks for Ultrafast Removal of Sulfaclozine

Advanced Science, EarlyView.
We report the rational design of artificial photocatalysts with asymmetrically coordinated dual‐metal centers and a tailored microenvironment, broadly applicable strategy is established for the synthesis of multivariate zirconium‐based metal–organic frameworks, offering a platform for precisely tuning active‐site configurations to optimize ...
Yuxin Lu, Yu‐Hang Li, Zhiyi Sun, Fanke Tong, Zelin Li, Sheng Wang, Shangkun Pei, Yi Li, Xiyan Xu, Chong‐Chen Wang, Bo Wang, Xiang Li   +11 more
wiley   +1 more source

Hessebius multiforaminis Pei, Ma, Zapparoli 2010

, 2014
Hessebius multiforaminis Pei, Ma, Zapparoli, 2010 Hessebius multiforaminis Pei, Ma & Zapparoli, 2010: 55, figs 1–8 Previous records. Xinjiang Uyghur Autonomous Region (Ali City) (Pei et al, 2010). Remarks. Only known from China.Published as part of
Hou, Xiaojie, Pei, Sujian, Gai, Yonghua, Zhu, Tiegang, Ma, Huiqin, Wu, Dayong   +5 more
core   +1 more source

Thermal‐Ionic Coupling in Transpiration‐Inspired Janus Nanofiber Membranes: Synergistic Dry‐Wet Interface Engineering for Solar‐Driven Electricity Generation

Advanced Science, EarlyView.
A transpiration‐inspired Janus nanofiber membrane creates a persistent dry‐wet interface that couples localized solar heating with hydration‐induced ion regulation. The asymmetric architecture sustains directional water and ion transport, suppresses salt accumulation, and enables simultaneous seawater evaporation and stable electricity generation ...
Qin Su, Haidi Wu, Tingting Zheng, Di He, Huaiguo Xue, Longcheng Tang, Yongqian Shi, Xuejun Lai, Jiefeng Gao, Wancheng Gu, Jun Yan   +10 more
wiley   +1 more source

Uncoupling Type I Interferon Benefits From Inflammatory Toxicity: Transformer‐Prioritized Precision Agonists for Potent and Safer Cancer Immunotherapy

Advanced Science, EarlyView.
A Transformer‐based AI framework, DLINP, screens millions of compounds to identify Co68, a cobalt‐pincer organometallic complex that biases TLR4‐MD2 signaling toward antitumor interferon activation while suppressing inflammatory toxicity through an early TLR4‐SYK‐STAT1 axis.
Xuefei Guo, Yang Zhao, Xianle Rong, Xingyu Chen, Xiao Wang, Tianyi Liu, Yunfei Xie, Yushu Zou, Pingsen Zhao, Qiang Liu, Fuping You   +10 more
wiley   +1 more source

RSF1‐Dependent PAR Turnover Promotes 53BP1 Liquid Condensate Formation at DNA Damage Sites

Advanced Science, EarlyView.
At sites of DNA damage, RSF1 recruits PARG to accelerate PAR turnover, triggering a switch from PAR‐driven condensates to 53BP1 condensates. This condensate transition enables p53‐dependent gene transcription and coordinates the DNA damage response.
Yungyeong Heo, Yonghyeon Kim, Nangyeong Hwang, Gwanho Sung, Sujin Jo, Yeonhu Lee, Ho‐Chul Kang, Jae‐Ho Lee, Yong Won Choi, Hyeseong Cho, Sunwoo Min   +10 more
wiley   +1 more source

New tumor-targeted nanosized delivery carrier for oligonucleotides: characteristics in vitro and in vivo

International Journal of Nanomedicine, 2011
Tianyang Zhou1,2, Xin Jia1, Huixiang Li3, Jin Wang3, Hongling Zhang1,2, Youmei A1,2, Zhenzhong Zhang1,21School of Pharmaceutical Sciences, 2Nanotechnology Research Center for Drugs, 3Department of Pathology, Medical School of Zhengzhou University ...
Zhou T, Jia X, Li H, Wang J, Zhang H, A Y, Zhang ZZ   +6 more
doaj  

(poly IC)PEI-PEG-EGF(+PEI-Mel) Complexes Selectively Kill U87MGwtEGFR Cells

, 2013
(A) Cells were seeded in duplicate onto a 96-well plate at a density of 5,000 cells in 0.2 ml of medium per well and grown overnight. Cells were then transfected as described [6,9] with poly IC at the indicated concentrations using either PEI-PEG-EGF or ...
Alexander Levitzki (32255), Manfred Ogris (60759), Alexei Shir (60758), Ernst Wagner (60760)   +3 more
core   +1 more source

Compact 9dBEs Enable Efficient and Precise Genome Editing in Mammalian Cells and In Vivo

Advanced Science, EarlyView.
As a compact type II‐D system, the Cas9d‐based platform holds great potential for in vivo applications. Through rational engineering, its derived base editors (9dBEs) enable efficient disease modeling while facilitating single‐vector AAV delivery for in vivo genome editing. These miniature tools offer a robust strategy for basic research and biomedical
Qingquan Xiao, Zhijin Tian, Luqi Weng, Kun Xu, Dingyi Han, Zhaowei Wu, Junnan Li, Shangpu Li, Qijing Zhang, Xiaohui Zhao, Guoling Li, Yinghui Wei, Zhen Gu   +12 more
wiley   +1 more source

Síntese de polietilenoiminas ramificadas decoradas com grupos hidrofóbicos e nucleosídeos e estudos de sua interação com dodecilsulfato de sódio e DNA [PDF]

, 2012
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciencias Fisicas e Matematicas, Programa de Pós-Graduação em Química, Florianópolis, 2012A poli(etilenoimina) (PEI) foi modificada por meio da alquilação com grupos n-alquila (n = 4, 6,
Bellettini, Ismael Casagrande
core