Results 161 to 170 of about 64,153 (313)

Ferritin Iron Mineralisation: Route of Fe3+ Transfer From the Ferroxidase Centre to the Inner Cavity of Human H‐Chain Ferritin

open access: yesAngewandte Chemie, EarlyView.
Proposed mechanism for Fe3+ transport from the FoC (sites 1 and 2) of human H‐chain ferritin following oxidation of the di‐Fe2+ form. Glu61, aided by the flexibility of its sidechain, plays a key role in coordinating Fe3+ at three sites (3, 4 and 5) that mark out the transit route.
Zinnia Bugg   +3 more
wiley   +2 more sources

Pelagic environments.

open access: yes, 2016
Pelagic sediments are chiefly composed of the microscopic skeletal remains of planktonic animals and plants, variously diluted by non-biogenic components. Such sediments may be carbonate-rich, silica-rich or clay-rich and they change in facies when traced laterally across the ocean and vertically through different bathymetric levels.
openaire   +1 more source

Liquid Jetting‐Based Miniature Robotic Navigation in Confined Fluidic Spaces

open access: yesAdvanced Intelligent Systems, EarlyView.
We introduce a new class of liquid‐jetting‐based miniature robots (JetBots) ranging in size from mm‐to‐cm, featuring a unified approach in design, fabrication, and actuation. They demonstrate fast locomotion (30.3 cm/s), rapid steering (648.8°/s), and diverse functions, such as puncturing soft materials and unlimited cargo sampling and delivery, paving
Debasish Roy, Tianlu Wang
wiley   +1 more source

Incorporation of Novel Synthetic Glycolipids in Liposomal Nanoparticles Affects Opsonization and In Vivo Clearance

open access: yesAngewandte Chemie, EarlyView.
We prepared five glycosylated liposomal nanoparticles (G‐LNPs) to investigate the role of glycosylation and protein corona in modulating the in vivo behavior of G‐LNPs. We show that IgG and complement C3 adsorption enhanced liposomal nanoparticle clearance, with IgG promoting subsequent C3 binding.
Yingjie Yu   +18 more
wiley   +2 more sources

Analyses of eye lens stable isotopes across ontogeny of trophically diverse freshwater salmonids. [PDF]

open access: yesPLoS One
Schumacher GT   +5 more
europepmc   +1 more source

PPO‐Based Reinforcement Learning for the Semi‐Active Vibration Control of MDOF Platform

open access: yesAI &Innovation, EarlyView.
ABSTRACT Aiming at the coupled vibration problem of a multi‐degree‐of‐freedom (MDOF) vibration isolation platform under eccentric excitation, this paper proposes a semi‐active vibration control strategy based on Proximal Policy Optimization (PPO) ‐based reinforcement learning (PPO RL).
Wei Huang, Jian Xu
wiley   +1 more source

Total Chemical Synthesis of Interleukin‐15 and Interleukin‐2: Taming Protein Hydrophobicity and Aggregation by a Versatile Solubilizing Strategy

open access: yesAngewandte Chemie, EarlyView.
A reducible solubilizing tag strategy (RST‐2.0) enables the synthesis, purification and ligation of difficult peptides while being readily removable just during folding, which overcomes the common challenges from protein hydrophobicity and aggregation. With this method, we achieved the first total synthesis of native and N‐glycosylated IL‐15 as well as
Jingwen Zeng   +4 more
wiley   +2 more sources

High‐elevation endemic plants predicted to lose habitat from changing climate in Washington State

open access: yesAmerican Journal of Botany, EarlyView.
Abstract Premise High‐elevation plants face unique challenges from potential climate change impacts that will likely require upslope migration into increasingly smaller suitable habitat. This situation is particularly acute for endemic species that by definition occupy small geographic ranges.
Nicholas L. Gjording   +4 more
wiley   +1 more source

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