Mediterranean Journal of Hematology and Infectious Diseases, 2021 Backround Data about the morphological changes of Covid-19 infection in peripheral blood smear are limited and association with clinical severity of the disease are not known yet.
Ilhami Berber +8 more
doaj +2 more sources
Myelodysplastic Syndrome With Trisomy 8 and Behçet Disease-Like Intestinal and Upper Gastrointestinal Involvement. [PDF]
Clin Case RepWe found an extremely rare case of upper gastrointestinal involvement in trisomy 8‐positive myelodysplastic syndrome. This is the first reported case of trisomy 8‐positive myelodysplastic syndrome with both upper and lower gastrointestinal involvement ...
Kawata Y +7 more
europepmc +3 more sources
Estudo da anomalia de Pelger-Huët em núcleo familiar Pelger-Huët anomaly study in a family [PDF]
Revista Brasileira de Hematologia e Hemoterapia, 2008 The Pelger-Huët anomaly is a dominant autosomal disease, characterized by the incomplete segmentation of the granulocytes nucleus without lost of the cellular function.
Patrícia H. O. Calderan +3 more
doaj +2 more sources
Young Woman with Unexplained Neutropenia and Neutrophils with Bilobed Nuclei: Marrow Findings
Case Reports in Hematology, 2023 A 27-year-old female with a history of chronic sinusitis was referred for the evaluation of asymptomatic neutropenia. The differential demonstrated a mild neutropenia, which eventually resolved on subsequent evaluation.
Martin Barnes +3 more
doaj +2 more sources
Alterations in nuclear structure promote lupus autoimmunity in a mouse model [PDF]
Disease Models & Mechanisms, 2016 Systemic lupus erythematosus (SLE) is an autoimmune disorder characterized by the development of autoantibodies that recognize components of the cell nucleus.
Namrata Singh +5 more
doaj +3 more sources
A homozygous lamin B receptor variant resulting in Pelger-Huët anomaly without skeletal dysplasia. [PDF]
NucleusThe lamin B receptor (LBR) is an inner nuclear membrane protein with a structural function affecting nuclear segmentation in neutrophils and an enzymatic function as a sterol reductase.
Hoffmann K +7 more
europepmc +2 more sources
Novel lamin B receptor mutation (c.561C > G) in a patient with Pelger-Huët anomaly: a case report. [PDF]
Front PediatrPelger-Huët anomaly (PHA), an autosomal dominant disorder characterized by abnormal granulocyte morphology, was first described in 1928. Mutations in the lamin B receptor (LBR) gene cause a phenotypic spectrum ranging from isolated PHA, PHA with mild ...
Yin J +6 more
europepmc +2 more sources
Myelodysplasia From Valproic Acid Resolved by Cessation. [PDF]
Case Rep HematolMyelodysplastic neoplasms (MDS) are clonal blood disorders that cause ineffective hematopoiesis, low blood counts, and a risk of progression to acute myeloid leukemia. Chemotherapy and radiation usually drive these changes, but a small set of medications, including valproic acid (VPA), can also produce reversible myelodysplastic features.
Ugwu C, Palma AU, Bhat R, Taneja A.
europepmc +2 more sources
Prevalence of hyposegmentation of granulocytes/Pelger-Huët anomaly in different canine breeds: a Bayesian approach. [PDF]
Front Vet SciPelger-Huët anomaly (PHA) is a benign congenital hematological disorder first observed in humans and occasionally reported in dogs. It has been mainly described in Australian Shepherd Dog (ASD) with a prevalence of 9.8–13% where, based on a genetic study,
Carli E, Salsecci E, Calleo R, Baldi I.
europepmc +2 more sources
Congenital Pelger-Huët anomaly in a Danish/Swedish Farmdog: case report. [PDF]
Acta Vet Scand, 2011 A 13 year old Danish/Swedish Farmdog from Denmark was evaluated in a veterinary clinic in Warsaw, Poland for evaluation of an orthopedic problem. Radiographs revealed spondylosis and degenerative vertebral disease, which responded to treatment with anti ...
Lukaszewska J, Allison RW, Stepkowska J.
europepmc +2 more sources