Results 51 to 60 of about 257,150 (173)

Pseudo Pelger-Huet - 1

, 2018
An image from a peripheral blood smear showing a hyposegmented neutrophil seen in a patient with Pseudo Pelger-Huet (100X oil immersion)
To, Michelle, Kwon, Gloria
core   +1 more source

Atypical chronic myeloid leukemia: From diagnosis to molecular features and therapeutic options

HemaSphere, Volume 9, Issue 12, December 2025.
ABSTRACT Atypical chronic myeloid leukemia (aCML) is a rare form of myelodysplastic (MDS)/myeloproliferative neoplasm (MPN) overlap disorder characterized by neutrophilic leukocytosis with circulating immature myeloid cells (IMC), frequent hepatosplenomegaly, and poor prognosis with high rates of leukemic transformation.
Alessandra Iurlo, Daniele Cattaneo, Umberto Gianelli, Francesco Passamonti   +3 more
wiley   +1 more source

Pseudo Pelger-Huet - 3

, 2018
An image from a peripheral blood smear showing a hyposegmented neutrophil in a patient with Pseudo Pelger-Huet (100X oil immersion)
To, Michelle, Kwon, Gloria
core   +1 more source

Mutations in the gene encoding the lamin B receptor produce an altered nuclear morphology in granulocytes (Pelger-Huet anomaly).

, 2002
Pelger-Huet anomaly (PHA; OMIM *169400) is an autosomal dominant disorder characterized by abnormal nuclear shape and chromatin organization in blood granulocytes.
Olins, A L, Reis, A, Hoffmann, K, Vaya, A, Ware, R E, Sotelo, C r, Olins, D E, Lucke, B, Lindner, T H, Sperling, K, Muller, D, Shultz, L D, Karl, H, Aznar, J, Herrmann, H, Dreger, C K, Kaps, R   +16 more
core   +3 more sources

Pseudo Pelger-Huet - 2

, 2018
An image from a peripheral blood smear showing a hyposegmented neutrophil in a patient with Pseudo Pelger-Huet (100X oil immersion)
To, Michelle, Kwon, Gloria
core   +1 more source

Anomalía de Pelger Hüet. A propósito. de un caso. Pelger-Hüet anomaly. Apropos of a case.

Revista Médica Electrónica, 2009
La anomalía de Pelger Hüet fue descrita inicialmente en 1928 por el médico holandés Pelger y su origen genético fue descubierto más tarde por el pediatra Hüet.
Adys Gutiérrez Díaz, Lourdes Díaz Naranjo, Luis Ramón Rodríguez, Juan Ramírez Díaz, Elizabeth Suárez García, Guillermo Montalván González   +5 more
doaj  

Clinical and Molecular Heterogeneity Underlying Monogenic Causes of Pediatric Diabetes Associated to Brain Developmental Disorders

Clinical Genetics, Volume 108, Issue 5, Page 495-510, November 2025.
A growing number of genetic variants linking non‐autoimmune diabetes to NDDs across different ages offer key insights about a common background of these phenotypes. These findings call for multidisciplinary approaches to care that integrate metabolic and neurological management in affected children.
Gabriele Di Pasquale, Camilla Valsecchi, Giulia Marie Smylie, Vincenzo Salpietro, Gian Vincenzo Zuccotti, Maurizio Delvecchio, Chiara Mameli   +6 more
wiley   +1 more source

Lamin B-receptor mutations in Pelger-Huët anomaly

, 2002
Pelger-Huet anomaly is an inherited abnormality of neutrophils, characterized by reduced nuclear segementation and an apparently looser chromatin structure. Following linkage studies in two families, the lamin B-receptor (LBR) was sequenced and mutations
Garner, C, Salvati, F, Rees, D C, Best, S, Thein, S L, Thien, S L, Chad Garner, Height, S, Swee Lay Thein, Steve Best, David C Rees, Sue Height, Kallo, J, Filippo Salvati, Juraj Kallo   +14 more
core   +1 more source

Evaluation of Absolute Neutrophil Count in COVID-19 Patients in a Tertiary Care Hospital

Medical Laboratory Journal, 2022
Background and objectives: Coronavirus disease 2019 (COVID-19) is a communicable disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
Harsha Jaykar, Mangala Nagare, Gauri Bhat   +2 more
doaj  

cTAGE5/MEA6 Regulates LBR Localization to Maintain Nuclear Envelope Integrity and Safeguard Against Aging

Aging Cell, Volume 24, Issue 10, October 2025.
cTAGE5 regulates LBR trafficking between the ER and the nucleus membrane to maintain the integrity of both the ER and the nuclear envelope. cTAGE5 KO results in LBR retention in the ER, reduced stability, and subsequent disruption of nuclear envelope integrity. ABSTRACT cTAGE5/MEA6 plays a pivotal role in COPII complex assembly, ER‐to‐Golgi trafficking,
Yaqing Wang, Pengyu Sun, Fuqiang Yang, Tiantian Ma, Junwan Fan, Lei Shi, Nan Li, Fei Gao, Kangmin He, Zhiheng Xu   +9 more
wiley   +1 more source