Results 151 to 160 of about 393,742 (342)

Artificial Receptor in Synthetic Cells Performs Transmembrane Activation of Proteolysis

open access: yesAdvanced Biology, EarlyView.
Transmembrane signaling is the hallmark of living cells and is among the highest challenges for the design of synthetic cells. Herein, an artificial receptor based on the chemistry of self‐immolative linkers is used to communicate information across the lipid bilayer, for transmembrane activation of enzymatic activity. Abstract The design of artificial,
Ane Bretschneider Søgaard   +7 more
wiley   +1 more source

Characterization and Optimization of Vesicle Properties in bioPISA: from Size Distribution to Post‐Assembly Loading

open access: yesAdvanced Biology, EarlyView.
The paper explores the creation and characterization of vesicles through biocatalytic Polymerization‐Induced Self‐Assembly (bioPISA), focusing on achieving size uniformity using centrifugation techniques. It examines the effects of stirring speed on vesicle morphology and analyses the internal polymer‐rich structure using fluorescence correlation ...
Andrea Belluati   +7 more
wiley   +1 more source

Light‐Triggered Protease‐Mediated Release of Actin‐Bound Cargo from Synthetic Cells

open access: yesAdvanced Biology, EarlyView.
TEV Prtoease‐mediated Releasable Actin‐binding Protein (TRAP) is a protein‐based platform consisting of a cargo tightly bound to reconstituted actin networks in synthetic cells which can be proteolyticly released from the bound actin, followed by its secretion through membrane translocation mediated by a cell‐penetrating peptide.
Mousumi Akter   +3 more
wiley   +1 more source

RhoA and Rac1 as Mechanotransduction Mediators in Colorectal Cancer

open access: yesAdvanced Biology, EarlyView.
Analysing RhoA and Rac1 protein levels in Colorectal cancer (CRC) samples under mechanical strain highlights their potential as diagnostic markers. Monitoring their activity could offer valuable insights into how cancer spreads, paving the way for new approaches to better understand and diagnose colorectal cancer.
Sharda Yadav   +5 more
wiley   +1 more source

Lactation Response to Artificially-Dehydrated and Pelleted Alfalfa Added to a Ration of Timothy-Grass Mixed Hay and Grain

open access: bronze, 1954
F. S. Warren   +5 more
openalex   +1 more source

Scaling Up Synthetic Cell Production Using Robotics and Machine Learning Toward Therapeutic Applications

open access: yesAdvanced Biology, EarlyView.
Synthetic cells (SCs) hold great promise for biomedical applications, but manual production limits scalability. This study presents an automated method for large‐scale SC synthesis, integrating robotic liquid handling and machine learning‐driven high‐throughput characterization.
Noga Sharf‐Pauker   +7 more
wiley   +1 more source

Smart Rubber Extrusion Line Combining Multiple Sensor Techniques for AI‐Based Process Control

open access: yesAdvanced Engineering Materials, EarlyView.
This publication presents a digitalization approach for a laboratory rubber extrusion line, employing innovative measurement methods and artificial intelligence (AI)‐based process control. The results demonstrate that the measurement systems are capable of detecting changes in the process and extrudate quality.
Alexander Aschemann   +18 more
wiley   +1 more source

Performance Evaluation of Upper‐Level Ontologies in Developing Materials Science Ontologies and Knowledge Graphs

open access: yesAdvanced Engineering Materials, EarlyView.
This article provides examples of ontology development in the materials science domain (use‐case of Brinell hardness testing) and gives ontology developers an overview for selecting their desired top‐level ontologies (e.g., BFO, EMMO, PROVO) by considering different evaluation parameters like semantic richness, domain coverage, extensibility ...
Hossein Beygi Nasrabadi   +3 more
wiley   +1 more source

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