Results 221 to 230 of about 44,126 (290)

De Novo Designed Minibinders Targeting the GDF15–GFRAL Axis Reverse Cancer Cachexia and Restore Anti‐Tumor Immunity

Advanced Science, Volume 13, Issue 51, 14 September 2026.
Tumor‐derived GDF15 drives cancer cachexia and suppresses antitumor immunity. Here, de novo designed minibinders targeting the GDF15–GFRAL interface achieve picomolar affinity and potent pathway blockade. The minibinders alleviate cachexia, restore CD8+ T‐cell infiltration, enhance anti–PD‐1 responsiveness, and provide survival benefits across tumor ...
Haitao Wang, Tianzhen Hua, Meiling Wang, Bingbing Meng, Yue Zhang, Chengxu Jiang, Yunhe Gao, Hongqi Yang, Jian Bo   +8 more
wiley   +1 more source

A novel device for studying temperature and touch interactions. [PDF]

J Neurosci Methods
Ramirez JC, Vergara J, Lin J, Chen J, Yau JM.   +4 more
europepmc   +1 more source

A Multimodal Haptic Feedback Interface with Thin‐Film Compliant Mechanism

Advanced Science, Volume 13, Issue 49, 3 September 2026.
Multimodal haptic devices can trigger different mechanoreceptors, enabling richer haptic information. This study presents an electromagnetic multimodal haptic device capable of delivering indentation, stretch, and vibration stimuli. The device is enabled by a novel polymer thin‐film compliant mechanism that provides high translational compliance along ...
Jingjing Wan, Emanuele Nicotra, James Davies, Kefan Zhu, Quang Anh Nguyen, Sinuo Zhao, Chi Cong Nguyen, Bibhu Sharma, Adrienne Ji, Hermione Truong, Patrick Pruscino, Tan Huynh, Phuoc Thien Phan, Hoang‐Phuong Phan, Nigel Hamilton Lovell, Thanh Nho Do   +15 more
wiley   +1 more source

Addendum to Nociception and pain in humans lacking a functional TRPV1 channel. [PDF]

J Clin Invest
Katz B, Zaguri R, Edvardson S, Maayan C, Elpeleg O, Lev S, Davidson E, Peters M, Kfir-Erenfeld S, Berger E, Ghazalin S, Binshtok AM, Minke B.   +12 more
europepmc   +1 more source

In‐Sensor Computing by Soft Threshold Logic Gates Under Different Humidity Conditions

Advanced Electronic Materials, Volume 12, Issue 17, 7 September 2026.
Soft nanocomposite materials, based on gold cluster‐assembled thin films implanted in polydimethylsiloxane substrate, can perform reliable processing in ambient environmental conditions. Humidity influences the resistive switching and computational capabilities of the nanocomposites, that can be used as multifunctional material combining sensing ...
Giacomo Nadalini, Paolo Milani, Francesca Borghi   +2 more
wiley   +1 more source

SenseCheQ: Home-based Nerve Function Self-Assessment using Autonomous Quantitative Sensory Testing

Gausden J, Dujmović M, Dunham JP, Thakkar B, Bennett T, Burgess C, Barraclough M, Young A, Whittaker RG, Robinson T, Colvin L, O’Neill A, Pickering AE.   +12 more
europepmc   +1 more source

Women and alcohol: A call to action. [PDF]

Alcohol Clin Exp Res (Hoboken)
McKee SA, Earnshaw VA, Epstein E, Hughes TL, Johnston AD, Lee CS, McCrady BS, Nixon K, Peltier MP, Roberto M, Scheer JR, Verplaetse T, Werner DF, Zakiniaeiz Y, Cosgrove KP.   +14 more
europepmc   +1 more source

Applicability limits of time-domain impedance spectroscopy for comprehensive thermoelectric characterization under heat leakage conditions. [PDF]

Sci Rep
Hasegawa Y, Kodama K.
europepmc   +1 more source