Results 61 to 70 of about 41,829 (290)

Aptamer‐Engineered Liposomal Platform Enables in Situ cDC1 Vaccination to Potentiate Immunotherapy in Prostate Cancer

open access: yesAdvanced Science, EarlyView.
Prostate cancer is immunologically ‘cold’, with scarce, dysfunctional type 1 conventional dendritic cells (cDC1s) that limit T cell priming. We introduce an aptamer‐targeted liposomedelivering FMS‐like tyrosine kinase 3 ligand (Flt3L) and chlorin e6 (Ce6). Ultrasound induces antigen release and cDC1s recruitment, creating an in situ cDC1 vaccine.
Jiayi Wang   +8 more
wiley   +1 more source

Self-calibrating 3D-ultrasound-based bone registration for minimally invasive orthopedic surgery

open access: yes, 2006
Intraoperative freehand three-dimensional (3-D) ultrasound (3D-US) has been proposed as a noninvasive method for registering bones to a preoperative computed tomography image or computer-generated bone model during computer-aided orthopedic surgery (CAOS)
C.S.K. Chan   +19 more
core   +1 more source

Lactation is Associated with Accelerated Postpartum Pelvic Floor Muscle Recovery in a Pregnant Simulated Birth Injury Model

open access: yesAdvanced Science, EarlyView.
ABSTRACT Healthy pelvic floor muscles (PFMs) are essential for proper pelvic floor function. The biggest risk factor for PFM dysfunction is injury sustained during vaginal childbirth, yet the factors that facilitate or impair PFM recovery from birth injury remain unknown.
Bianca L. Peña   +7 more
wiley   +1 more source

Evaluation of sarcoidosis with multiple bone lesions using both bone scintigraphy and FDG-PET/CT: A case report

open access: yesRespiratory Medicine Case Reports
Sarcoidosis is a systemic granulomatous disease; however, the incidence of bone sarcoidosis is relatively rare. The short tubular bones of the hands and feet are most frequently affected, while the vertebrae and the pelvic bones are rarely involved.
Naohiro Kadoma   +7 more
doaj   +1 more source

Incidentally Diagnosed Osteopoikilosis: A Case Report

open access: yesTürk Osteoporoz Dergisi, 2017
Osteopoikilosis is a rare bone dysplasia. Patients are generally asymptomatic and are frequently identified during radiological imaging by coincidence. The epiphysis and metaphysis of the long bones, the phalanges and pelvic bones are the localizations ...
Mustafa Reşorlu   +3 more
doaj   +1 more source

Mean Subpubic Angle of Patients Visiting Department of Radiodiagnosis of a Tertiary Care Hospital: A Descriptive Cross-sectional Study

open access: yesJournal of Nepal Medical Association, 2022
Introduction: The subpubic angle in the pelvis is most often used to estimate the sex with a higher degree of accuracy. Despite the anthropological and obstetric importance of the subpubic angle, only a few studies exist in the Nepalese population.
Ruku Pandit   +2 more
doaj   +1 more source

Notes on the anatomy, positioning and homology of the pelvic bones in small cetaceans (Cetacea, Delphinidae, Pontoporiidae)

open access: yes, 2004
This report analyzes the variations in positioning and orientation of the pelvic bones in small cetaceans, and contributes to establishing a possible homology based on the attachment of the abdominal musculature. Seven carcasses of three cetacean species
P. C. Simões-Lopes   +3 more
core   +1 more source

CCT2 Promotes Prostate Cancer Progression Through EIF3F‐Dependent Stabilization of FASN

open access: yesAdvanced Science, EarlyView.
ABSTRACT Prostate cancer (PCa) is increasingly recognized to be driven by dysregulated lipid metabolism. Although fatty acid synthase (FASN) is highly expressed in PCa, the mechanisms governing FASN protein stability and its functional integration into oncogenic lipid metabolism remain poorly defined.
Shun Xu   +13 more
wiley   +1 more source

Morphological variations of the femoral head-neck junction in historical skeletal material [PDF]

open access: yesPeerJ
Background Poirier’s facet, Allen’s fossa and femoral plague are the main morphological variations of the femoral head-neck junction. The study aimed to answer questions about the association between the shape of the proximal end of the femoral bone and ...
Anna Myszka, Anna Maria Kubicka
doaj   +2 more sources

Long‐Term Follow Up of Two Patients With Variants in the Cluster 1031‐1159 of TRRAP Gene: Expanding the Phenotype of Developmental Delay With or Without Dysmorphic Facies and Autism

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT The transformation/transcription domain‐associated protein (TRRAP) gene encodes a large multidomain protein, a member of the phosphatidylinositol 3‐kinase‐related kinase (PIKK) family. TRRAP is a component of the histone acetyltransferase (HAT) complex, and it plays an important role in gene transcription, DNA repair, and cell‐cycle regulation.
Roseli Maria Zechi‐Ceide   +10 more
wiley   +1 more source

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