FBXW7β loss-of-function enhances FASN-mediated lipogenesis and promotes colorectal cancer growth
Signal Transduction and Targeted Therapy, 2023 Continuous de novo fatty acid synthesis is required for the biosynthetic demands of tumor. FBXW7 is a highly mutated gene in CRC, but its biological functions in cancer are not fully characterized.
Wenxia Wei +18 more
doaj +1 more source
Archives of Gynecology and Obstetrics, 2021 Although pregnancy and childbirth are physiological processes they may be associated with pelvic floor disorders. The aim of this study was to evaluate the influence of pelvic floor muscle training on postpartum pelvic floor and sexual function of ...
Sabine Schuetze +6 more
semanticscholar +1 more source
Cell Communication and Signaling, 2022 Background The screening biomarkers for early detection of colorectal cancer (CRC) is lacking. The aim is to identify epigenetic silenced genes and clarify its roles and underlying mechanism in CRC.
Zixu Yuan +10 more
doaj +1 more source
High Transverse Vaginal Septum with Vaginal and Cervical Agenesis in a 13-Year-Old Female: A Case Report [PDF]
Journal of Midwifery & Reproductive Health, 2023 Background & aim: A vaginal septum is a condition in which the wall of the tissue dividing vagina does not resolve completely. This complication can be transverse and longitudinal.
Maryam Deldar Pesikhani +4 more
doaj +1 more source
Biomechanical trade-offs in the pelvic floor constrain the evolution of the human birth canal
Proceedings of the National Academy of Sciences of the United States of America, 2021 Significance The relatively small human birth canal has arisen from an evolutionary trade-off between multiple antagonistic selective forces. We present evidence that a large pelvic floor is disadvantageous for maintaining continence and supporting the ...
E. Stansfield +3 more
semanticscholar +1 more source
Short term outcomes of Laser Pile Ablation (LPA) to treat II-III degree symptomatic hemorrhoidal disease. [PDF]
Iranian Journal of Colorectal Research, 2021 Introduction The aim of this study is to assess the outcomes of Laser Pile Ablation (LPA) in patients affected by II-III degree symptomatic hemorrhoidal disease.
Francesco Cantarella +2 more
doaj +1 more source
Urinary incontinence related to perineal muscle strength in the first trimester of pregnancy: cross-sectional study [PDF]
, 2014 Objective To analyze pelvic floor muscle strength (PFMS), urinary continence and quality of life related to urinary incontinence (UI) of women in the first trimester of pregnancy.
Abrams P +33 more
core +8 more sources
PHYSIOTHERAPY FOR THE PELVIC FLOOR
Australian Journal of Physiotherapy, 1981 The inefficiencies of the physiotherapy profession in its attitude to the treatment of pelvic floor insufficiency and urinary stress incontinence are discussed, together with a description of the different types of urinary stress incontinence, their causes and a brief outline of the anatomy of the pelvic floor.
D.R. O'Keefe, Pauline Chiarelli
openaire +3 more sources
Pelvic floor disorders in gynecological malignancies. An overlooked problem? [PDF]
, 2018 Cervical, endometrial, ovarian, vulvar, and vaginal cancers affect women of a broad age spectrum. Many of these women are still sexually active when their cancer is diagnosed.
Bodean, Oana M. +7 more
core +3 more sources
Altered resting state neuromotor connectivity in men with chronic prostatitis/chronic pelvic pain syndrome: A MAPP: Research Network Neuroimaging Study. [PDF]
, 2015 Brain network activity associated with altered motor control in individuals with chronic pain is not well understood. Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS) is a debilitating condition in which previous studies have revealed altered ...
Apkarian, A Vania +18 more
core +1 more source