Results 61 to 70 of about 165,151 (264)

A large-scale multi-ancestry genome-wide association study of chronic prostatitis/chronic pelvic pain syndrome in men

Nature Communications
Chronic prostatitis/chronic pelvic pain syndrome is common, and it impacts men’s health and quality of life. The genetic basis of this condition remains largely unknown.
Sara Brin Rosenthal, Adam X. Maihofer, Caroline M. Nievergelt, Daniel Dochtermann, Armand Gerstenberger, Thomas Whisenant, Saiju Pyarajan, Kristina Allen-Brady, John N. Krieger, Million Veteran Program, Niloofar Afari, Marianna Gasperi   +11 more
doaj   +1 more source

Gephyrin Neurological Autoimmunity

Annals of Neurology, EarlyView.
Gephyrin is a postsynaptic scaffold protein essential for inhibitory neurotransmission. Gephyrin‐immunoglobulin G (IgG) was reported, decades ago, in a single case of paraneoplastic stiff‐person‐like syndrome, but its broader clinical relevance remains unknown.
Maria Chiara Pantuliano, Friederike A. Arlt, Naomi Arenson, Irena Dujmovic Basuroski, Divyanshu Dubey, Connie E. Lesnick, John R. Mills, Sean J. Pittock, Anastasia Zekeridou, Michael A. Lane, Andrew McKeon   +10 more
wiley   +1 more source

The mechanism of labor in nonhuman primates: A look inside

The Anatomical Record, EarlyView.
Abstract While in humans, the flexed position of the fetus and its rotating course down the birth canal are well documented, in other primates the mechanism of labor is unknown. Despite the lack of comparative data, it is commonly assumed that the human obstetric mechanism is unique, and anthropologists have disputed when and why the transition to the ...
Melissa K. Stoller
wiley   +1 more source

Does progestin-only contraceptive use after pregnancy affect recovery from pelvic girdle pain? A prospective population study.

PLoS ONE, 2017
ObjectiveTo estimate associations of progestin-only contraceptives with persistent pelvic girdle pain 18 months after delivery.MethodsProspective population based cohort study during the years 2003-2011. We included 20,493 women enrolled in the Norwegian
Elisabeth Krefting Bjelland, Katrine Mari Owe, Hedvig Marie Egeland Nordeng, Bo Lars Engdahl, Per Kristiansson, Siri Vangen, Malin Eberhard-Gran   +6 more
doaj   +1 more source

Human evolution and the obstetrical dilemma: The pelvic floor hypothesis

The Anatomical Record, EarlyView.
Abstract Human childbirth is mechanically difficult because a large‐headed, broad‐shouldered fetus must pass through a comparatively narrow, twisted bony birth canal. Traditional explanations of this “obstetrical dilemma” emphasize the role of bipedal locomotion in inhibiting the evolution of a wider, more spacious pelvis.
Barbara Fischer, Ekaterina Stansfield
wiley   +1 more source

Is it time to agree upon a standardised approach to the assessment of contributing factors and impacts of adolescent pelvic pain?

Journal of Obstetrics and Gynaecology
Background A biopsychosocial approach to the understanding of pelvic pain is increasingly acknowledged. However, there is a lack of standardised instruments – or their use – to assess risk factors and their impact on pelvic pain in both clinical and ...
Dehlia Moussaoui, Olivia G. Farrell, Sonia R. Grover   +2 more
doaj   +1 more source

Significant Clinical Improvements Following Arthroscopic Iliopsoas Fractional Lengthening After Total Hip Arthroplasty: A Prospective Multicenter Study

Arthroscopy, Sports Medicine, and Rehabilitation, EarlyView.
Purpose To prospectively investigate subjective anterior groin pain, patient‐reported outcome measures, complications, reoperation rates, and hip flexion strength after arthroscopic iliopsoas fractional lengthening. Methods From 2023 to 2025, patients with persistent groin pain after total hip arthroplasty refractory to conservative management ...
Brandon Cabarcas, Sanathan Iyer, Sandeep Yanamala, Jason Ina, Alexander Bishop, Adam V. Daniel, Bruce A. Levy, Mario Hevesi   +7 more
wiley   +1 more source

Tissue‐Specific and Spatially Dependent Metabolic Signatures Perturbed by Injury in Male and Female Mice

Arthritis &Rheumatology, EarlyView.
Objective Osteoarthritis, the leading cause of disability worldwide, disproportionately affects women, yet sex remains an overlooked determinant. This disparity stems from sex‐specific differences in injury susceptibility—a major risk factor for disease.
Hope D. Welhaven, Avery H. Welfley, Priyanka P. Brahmachary, Mark Greenwood, Donald F. Smith, Brian Bothner, Ronald K. June   +6 more
wiley   +1 more source

Factors associated with chronic pelvic pain in women with endometriosis: A national study on clinical and sociodemographic characteristics, lifestyles, quality of life, and perceptions of quality of care, during the COVID-19 pandemic

Women's Health
Background: Endometriosis is a persistent inflammatory condition that affects women of reproductive age and causes pelvic pain. Chronic pelvic pain is a chronic regional pain syndrome involving the pelvic area.
Vincenza Cofini, Mario Muselli, Emiliano Petrucci, Chiara Lolli, Erika Pelaccia, Maurizio Guido, Franco Marinangeli, Leila Fabiani, Stefano Necozione   +8 more
doaj   +1 more source

Functional Impact of Structural Damage in Psoriatic Arthritis: Insights from a Prospective Cohort Study

Arthritis &Rheumatology, EarlyView.
Objective To examine the association between radiographic structural damage and physical function (PF) in psoriatic arthritis (PsA). Methods Data were analyzed from a large longitudinal PsA cohort. PF was measured using the Health Assessment Questionnaire (HAQ, 0–3) and Short Form‐36 PF subscale (SF‐36, 0–100); radiographic joint damage was measured ...
Pankti Mehta, Shangyi Gao, Virginia Carrizo Abarza, Fadi Kharouf, Daniel Pereira, Richard J. Cook, Dafna D. Gladman, Vinod Chandran, Denis Poddubnyy   +8 more
wiley   +1 more source