Results 251 to 260 of about 423,038 (361)

Neoadjuvant chemoradiotherapy with capecitabine and irinotecan guided by UGT1A1 status in patients with locally advanced rectal cancer: 5‐year update of the CinClare trial

open access: yesCancer Communications, EarlyView.
Abstract Background The optimal regimen and chemotherapy intensity are still under investigation for neoadjuvant treatment of locally advanced rectal cancer (LARC). The CinClare trial has demonstrated improved pathologic complete response (pCR) with the addition of irinotecan to neoadjuvant chemoradiotherapy (CRT) guided by uridine diphosphate ...
Zhen Zhang   +24 more
wiley   +1 more source

Advances in radiopharmaceuticals for cancer radiotheranostics: CCK2R targeting as a paradigm for translational innovation

open access: yesCancer Communications, EarlyView.
Abstract Radiopharmaceuticals are reshaping the landscape of cancer therapy, offering a unique theranostic advantage that is becoming increasingly central to precision medicine. By labeling the same molecular scaffold with different radionuclides, these agents enable seamless integration of diagnostic imaging and targeted therapy.
Jing Li   +6 more
wiley   +1 more source

Harnessing Nature: Computational and Experimental Insights Into Ipomoea obscura Metabolites for Bladder Cancer Therapy

open access: yesChemistry &Biodiversity, EarlyView.
ABSTRACT Ipomoea obscura (L.), a medicinal plant from the Convolvulaceae family, has been traditionally used to treat various ailments. This study evaluated the in vitro cytotoxicity of its ethanolic leaf extract against human bladder cancer T24 cells and investigated its phytochemical constituents through computational methods.
Saravana Prabha Poochi   +8 more
wiley   +1 more source

Redo‐Transcatheter Aortic Valve Replacement With a 26 mm Sapien Valve in a 26 mm Evolut Valve to Correct Significant Paravalvular Leak via Transcarotid Access

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT An 84‐year‐old man with multiple comorbidities including severe aortic stenosis, heart failure with a reduced ejection fraction, severe peripheral artery disease with prior bilateral iliac artery stents, and trifascicular block presented for evaluation for aortic valve replacement.
Charlene L. Rohm   +4 more
wiley   +1 more source

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