Results 51 to 60 of about 291,535 (278)

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Luxación de la prótesis bipolar de cadera en adultos mayores. Comparación de los abordajes posterolateral y anterolateral

Revista de la Asociación Argentina de Ortopedia y Traumatología
Objetivo: Comparar el riesgo de luxación de la prótesis bipolar de cadera con los abordajes posterolateral y anterolateral en el tratamiento de una fractura de cuello femoral.
Arturo Aguilar Maldonado, José Luis Lecca Zavaleta   +1 more
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Long-term outcomes of the modified Dunn procedure in moderate and severe slipped capital femoral epiphysis: a prospective case series with 7-year follow-up

Journal of Orthopaedics and Traumatology
Introduction Slipped capital femoral epiphysis (SCFE) is the most common hip disorder in adolescents and may lead to femoroacetabular impingement, early osteoarthritis, and long-term functional disability if inadequately treated.
Mahmoud Fahmy, Ahmed Hazem Abdelazeem, Mostafa Ahmed Shawky   +2 more
doaj   +1 more source

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

Molecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau, Daniel Pincher, Clifford Young, Nicholas Chappell, Noor A. Lokman, Parul Mittal, Leigh Donnellan, Martin K. Oehler, Doug A. Brooks, Peter Hoffmann   +9 more
wiley   +1 more source

Drilling and bone marrow injection in avascular necrosis of femoral head: A case series

Journal of Orthopaedic Reports
Background: The extant data do not yet permit definitive conclusions regarding the efficacy of the combined approach of concentrate bone marrow aspirate injection and core decompression as a treatment modality for avascular necrosis (AVN) of the femoral ...
Ahmed Farahat, Ahmed Hazem, Amr Hesham, Ahmad Azzam   +3 more
doaj   +1 more source

A Low Psoas Muscle Index Was Associated With a Poorer Overall Survival in Patients Who Underwent Percutaneous Nephrostomy

Aging and Cancer, EarlyView.
In patients with malignant ureteral obstruction undergoing percutaneous nephrostomy, sarcopenia defined by a low psoas muscle index was independently associated with poor overall survival on multivariate Cox regression analysis, suggesting that preoperative assessment of psoas muscle index may aid prognostic stratification in this population.
Kota Shimokihara, Takashi Kawahara, Kazuhide Makiyama, Hiroji Uemura   +3 more
wiley   +1 more source

Delayed fixation of neglected acetabular fractures: clinical challenges and mid-term outcomes of a prospective case series

Journal of Orthopaedic Surgery and Research
Objective Neglected acetabular fractures, defined as those not addressed surgically within three weeks of injury, pose significant technical and prognostic challenges due to chronic displacement, malunion, and soft tissue contracture. This study aimed to
Mahmoud Fahmy, Hazem Abdelazeem, Ahmed Hazem Abdelazeem, Mostafa Ahmed Shawky   +3 more
doaj   +1 more source

Cuerpos extraños ingeridos intencionalmente por un prisionero. Informe de caso

Medisur, 2021
La ingestión intencional de cuerpos extraños es frecuente entre prisioneros. Es un fenómeno asociado a un aumento de la morbimortalidad y los costos. Generalmente no requiere de intervención específica, aunque pueden aparecer complicaciones severas, que ...
Frank Yasel Leyva Vázquez, Abel Ernesto Ruiz de Villa Suárez, Daniel Alejandro Tello Duany   +2 more
doaj  

A Radiological Study on the Trabecular Pattern in the Upper End of the Femur in Post-Menopausal Women [PDF]

Journal of Clinical and Diagnostic Research, 2013
Objective: Anatomically, the upper end of the femur is a common site for osteoporosis. Therefore, The trabecular pattern in the upper end of femur is analyzed on the basis of the presence or absence, the relative number and density of the trabeculae ...
Veena Vidya Shankar , Jayanthi V, Srinath M.G., Roopa Kulkarni   +3 more
doaj   +1 more source