Results 81 to 90 of about 291,535 (278)

Aptamer‐Engineered Liposomal Platform Enables in Situ cDC1 Vaccination to Potentiate Immunotherapy in Prostate Cancer

Advanced Science, EarlyView.
Prostate cancer is immunologically ‘cold’, with scarce, dysfunctional type 1 conventional dendritic cells (cDC1s) that limit T cell priming. We introduce an aptamer‐targeted liposomedelivering FMS‐like tyrosine kinase 3 ligand (Flt3L) and chlorin e6 (Ce6). Ultrasound induces antigen release and cDC1s recruitment, creating an in situ cDC1 vaccine.
Jiayi Wang, Xuan Wang, Xinfeng Dai, Linxin Tian, Wencheng Shen, Xueliang Liu, Wei Xue, Jiahua Pan, Yu Yang   +8 more
wiley   +1 more source

STRUCTURAL ANALYSIS OF THE PELVIC GIRDLE BEFORE AND AFTER HIP REPLACEMENT PROCEDURE

Наука и техника, 2018
The paper presents the results of a preliminary study on the structural analysis of the pelvic girdle, comparing results for the analysis performed before and after the hip replacement procedure with taking into account changes in the mechanical ...
Ja. Zubrzycki, R. Karpinski, L. Jaworski, A. M. Ausiyevich, N. Smidova   +4 more
doaj   +1 more source

Regulating Cells Fate and Function to Facilitate Bone Regeneration via Designing Programmable Bio‐Interactive Materials

Advanced Science, EarlyView.
This article aims to elucidate the biological mechanisms of bone repair and the evolution of material design, highlighting key cellular and molecular processes. It further proposes strategies and prospects for programmable bio‐interactive materials, which enable precisely guided bone tissue regeneration by dynamically regulating cell behavior and the ...
Qingrui Fan, Fuming Cao, Junqiang Mao, Pengbin Yin, Licheng Zhang, Jianjun Wang, Peifu Tang   +6 more
wiley   +1 more source

Collapsed membranes within pelvic cyst: What is the diagnosis?

Clinical Case Reports, 2017
Key Clinical Message Collapsed membranes and daughter cysts are pathognomonic for hydatid cysts on imaging. The comma‐shaped lesions, visible within the hydatid cyst in sagittal view of MRI, are collapsed membranes.
Seyed Ali Dehghan Manshadi, Omid Rezahosseini, Sadegh Saberi, Faeze Salahshour, Shahrzad Mahdavi Izadi   +4 more
doaj   +1 more source

Radiographic Evaluation of Greater Sciatic Notch for Sex Determination: A Cross-sectional Study from Sri Ganganagar, Rajasthan, India [PDF]

Journal of Clinical and Diagnostic Research
Introduction: Sex estimation forms a fundamental step in forensic anthropology, bioarchaeology and medicolegal identification. The pelvis is considered the most reliable skeletal element for this purpose, with the Greater Sciatic Notch (GSN) being one of
Rasalika Miglani, Parveen Kumar Sharma, Vijay Kumar Dayma, Nikhil Sharma, Aakanksha Arora   +4 more
doaj   +1 more source

Lactobacillus‐Loaded Bioadhesive Hydrogel with Prolonged Retention and Microenvironmental Remodeling for Endometrial Repair and Fertility Restoration

Advanced Science, EarlyView.
A bioactive adhesive hydrogel capable of long‐term uterine retention (>14 days) and local microenvironment modulation is developed by straightforward integration of α‐lipoic acid, L‐arginine, tannic acid, and Lactobacillus johnsonii, which can markedly enhance endometrial repair and restore fertility in a rat model of endometrial injury.
Lifa Chen, Hui Zhou, Yifei Li, Yi Liang, Yifan Zhang, Huiyu Huang, Qiuxian Xie, Youchen Tang, Huixia Ye, Yu Zhang   +9 more
wiley   +1 more source

Autophagy Orchestrates Anti‐Tumor Immunity to Enhance Chemosensitivity via the FBXW2/C/EBPβ/TIMP‐2 Axis in Colorectal Cancer

Advanced Science, EarlyView.
Chemotherapy leverages tumor‐cell autophagy to reshape the colorectal cancer immune microenvironment. Autophagy degrades FBXW2 to promote C/EBPβ‐mediated TIMP‐2 transcription and MMP‐9 suppression, driving intra‐tumoral CD8+ T‐cell infiltration. Targeting MMP‐2/9 or restoring TIMP‐2 overcomes chemo‐resistance in autophagy‐deficient tumors. ABSTRACT The
Bing Cheng, Chaoying Wei, Zhitong Niu, Jinxin Chen, Guojie Long, Yingzhen Weng, Qiufeng Liu, Yue Jiang, Panpan Wang, Ronghua Zhang, Qiang Yu, Xiaojian Wu, Wenyu Wang   +12 more
wiley   +1 more source

Smaller Ischiofemoral Space Is Associated With Proximal Hamstring Injuries. [PDF]

Arthrosc Sports Med Rehabil
Purpose To develop a reference ischiofemoral space (IFS) value for patients with proximal hamstring injuries (HSI) and to compare it with individuals without proximal hamstring pathology. Methods We retrospectively collected the data from our institution. Patients aged 18 years or older with a proximal HSI were included.
Itthipanichpong T, Retzky J, Curran P, Menta SV, Ranawat AS.   +4 more
europepmc   +2 more sources

DIXDC1 Promotes Lymphatic Metastasis and Resistance to Cuproptosis in Bladder Cancer Through Mediating DLAT

Advanced Science, EarlyView.
DIXDC1 drives bladder cancer progression by binding and stabilizing DLAT. This axis enhances NEK7 and CCNE2 mRNA stability to promote proliferation and lymphatic metastasis, while limiting copper‐induced DLAT oligomerization to reduce cuproptosis sensitivity, identifying DIXDC1 as a potential target linking metastasis with cuproptosis resistance ...
Hongqiong Li, Liang Cheng, Xiaole Lu, Haonan Dong, Shi Fu, Hongjin Shi, Mingsheng Liu, Chenwei Yang, Yuhang Huang, Zehua Chen, Yawei Zhang, Kaiwen Jie, Xiaoyue Zhang, Xiang Kui, Xinni Ye, Siting Chen, Xu Chen, Haifeng Wang   +17 more
wiley   +1 more source

[Hydatidosis of the pelvis].

Archivos uruguayos de medicina, cirugia y especialidades, 2004
Presented at session 13th August ...
openaire   +3 more sources