Results 41 to 50 of about 18,647 (241)

Tocilizumab for severe and refractory mucous membrane pemphigoid. [PDF]

J Eur Acad Dermatol Venereol
Elevated IL‐6 levels identified in mucous membrane pemphigoid support IL‐6 blockade, with tocilizumab demonstrating clinical benefit in nine patients with severe and refractory mucous membrane pemphigoid. Abstract Background Mucous membrane pemphigoid (MMP) is a rare autoimmune blistering disease involving mucous membranes with a potentially ...
Tedbirt B, Maho-Vaillant M, Gueudry J, Golinski ML, Marcaillou M, Bergeret B, Chambon G, Bouchetemble P, Bekri S, Tebani A, Maillard H, Morice C, Vautier A, Libert EP, Le Roux-Villet C, Carrette M, Boyer O, Hébert V, Calbo S, Gillibert A, Joly P.   +20 more
europepmc   +2 more sources

Paraneoplastic bullous pemphigoid – A sign of clear cell renal carcinoma

Urology Case Reports, 2020
Paraneoplastic bullous pemphigoid is a rare paraneoplastic syndrome. Rash is pruritic, with erythematous eruption of large subepidermal bullae over skin and often mucosal surfaces.
Stuart R. Jackson, Jakob Koestenbauer, Adam P. Carroll, Than-Htike Oo, Shaun Chou, Balasubramaniam Indrajit   +5 more
doaj   +1 more source

SARS-CoV-2 infections in patients with autoimmune blistering disorders: A case series and retrospective analysisCapsule Summary

JAAD International, 2022
Background: Autoimmune blistering disorders (AIBDs) are rare, potentially life-threatening conditions often requiring immunosuppression. Throughout the SARS-CoV-2 pandemic, infection risk and mortality in patients with AIBDs are unknown.
Kimberly F. Breglio, MD, DPhil, Melissa M. Sarver, BS, Russell P. Hall, III, MD, Anne L. Marano, MD   +3 more
doaj   +1 more source

Safety outcomes of antidiabetic medications: A comprehensive review of the EU summaries of product characteristics and international clinical practice guidelines

British Journal of Clinical Pharmacology, EarlyView.
Aims Information on the safety profile of antidiabetic medications is essential for informed treatment decisions in type 2 diabetes mellitus. Although this information is available in regulatory documents of individual drugs, a comprehensive overview across all approved antidiabetics is lacking.
David Liang, Daniala L. Weir, Safana Thevasahayam, Vera H. M. Deneer, Arno Siebes, Helga Gardarsdottir   +5 more
wiley   +1 more source

The role of inflammation and fibroblasts in conjunctival scarring in ocular mucous membrane pemphigoid [PDF]

, 2009
Ocular mucous membrane pemphigoid (ocular MMP) is a visually devastating disease where up to 30% of patients become blind due to the consequences of conjunctival inflammation and aggressive fibrosis.
Saw, V.P.J.
core  

Periplakin, a novel component of cornified envelopes and desmosomes that belongs to the plakin family and forms complexes with envoplakin [PDF]

, 1997
The cornified envelope is a layer of transglutaminase cross-linked protein that is assembled under the plasma membrane of keratinocytes in the outermost layers of the epidermis.
Christiana Ruhrberg, Hajibagheri, MAN, Parry, DAD, Watt, FM, Ruhrberg, C, M.A. Nasser Hajibagheri, David A.D. Parry, Fiona M. Watt   +7 more
core   +1 more source

Pemphigoid gestationis

Ugeskrift for Læger
Pemphigoid gestationis (PG) is a rare autoimmune skin disorder which occurs during pregnancy. PG was first described as herpes gestationis in 1872, though it is not related to herpes virus. It typically presents in the second or third trimester and, rarely, post-partum.
Andersen, Anne-johanne, Thormann, Henrik, Kamaleswaran, Shailajah, Lorentzen, Henrik   +3 more
openaire   +3 more sources

Pemphigoid gestationis [PDF]

Clinical Case Reports, 2018
Key Clinical Message Pemphigoid gestationis is a rare autoimmune skin disorder emerging exclusively during pregnancy. Topical and oral glucocorticoids as well as oral antihistamines are the standard medications administered during pregnancy, aiming to relieve pruritus and to suppress extensive blister formation.
Ioannis K. Papapanagiotou, Sotiria Tsagouri, Chrysa G. Liakou, Alexandros Besharat, Nikistratos Vogiatzis, Konstantinos Ntzeros, Evangelos Petrakis, Pelopidas Koutroumanis, Nikolaos Thomakos, Dimitrios Loutradis   +9 more
openaire   +3 more sources

Treatment‐Related Adverse Events and Health‐Related Quality of Life Associated With Immune Checkpoint Inhibitor Treatment for Mucosal Head and Neck Squamous Cell Carcinoma: A Scoping Review

Head &Neck, EarlyView.
ABSTRACT Background Supportive care needs of patients receiving immune checkpoint inhibitors (ICIs) for head and neck squamous cell carcinoma (HNSCC) are ill‐defined. Hence, known treatment‐related adverse events (TRAEs) and health‐related quality of life (HRQoL) associated with ICI treatment for HNSCC were examined to inform future supportive care ...
N. D. O'Donnell, E. C. Ward, L. R. Wishart, R. Perera, C. Barrett, K. A. Edmiston, E. Mitchell, A. Pigott, R. Pitt, K. Russell, B. A. Chan, R. Ladwa   +11 more
wiley   +1 more source

Detection of linear IgE deposits in bullous pemphigoid and mucous membrane pemphigoid: a useful clue for diagnosis

, 2011
Bullous pemphigoid (BP) is an autoimmune subepidermal blistering disease of the skin associated with IgG autoantibodies to BP180 and BP230, while mucous membrane pemphigoid (MMP) comprises a heterogeneous group of autoimmune blistering diseases ...
Beltraminelli, H, S. Yayli, M. Horn, Borradori, L, L. Borradori, H. Beltraminelli, Z. Beleznay, Pelivani, N, Yayli, S, N. Pelivani, Horn, M, Wirthmüller, U, U. Wirthmüller, Beleznay, Z   +13 more
core   +1 more source