Results 81 to 90 of about 24,870 (249)

A Case for Anti‐IgE Vaccination

open access: yesAllergy, EarlyView.
ABSTRACT Immunoglobulin E (IgE) plays a central role in allergic diseases by binding to the high‐affinity receptor FcεRI on mast cells and basophils, where allergen‐induced crosslinking triggers potent inflammatory responses. Various mechanisms by which IgE responses are generated and functionally regulated remain elusive despite many years of research.
Paul Engeroff   +3 more
wiley   +1 more source

Emerging Topical and Systemic JAK Inhibitors in Dermatology [PDF]

open access: yes, 2019
Accumulating data on cellular and molecular pathways help to develop novel therapeutic strategies in skin inflammation and autoimmunity. Examples are psoriasis and atopic dermatitis, two clinically and immunologically well-defined disorders.
Ghoreschi, Kamran   +2 more
core   +1 more source

Skin Fragility and Hyperpigmentation in a Patient With HIV

open access: yes
JEADV Clinical Practice, EarlyView.
Catalina Retamal   +2 more
wiley   +1 more source

Limbal Fibroblasts Maintain Normal Phenotype in 3D RAFT Tissue Equivalents Suggesting Potential for Safe Clinical Use in Treatment of Ocular Surface Failure. [PDF]

open access: yes, 2014
Limbal epithelial stem cell deficiency can cause blindness, but transplantation of these cells on a carrier such as human amniotic membrane can restore vision. Unfortunately, clinical graft manufacture using amnion can be inconsistent. Therefore, we have
Dale, SB, Daniels, JT, Massie, I
core   +1 more source

Erosive pustular dermatosis of the lower legs (EPDL): A rarely diagnosed neutrophilic dermatosis of the elderly

open access: yesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Erosive pustular dermatosis of the lower legs (EPDL) is a rarely diagnosed, chronic inflammatory skin disease that occurs predominantly in elderly people. Predisposing factors include skin atrophy, chronic venous insufficiency, and trauma. Although the pathogenesis of EPDL has not yet been conclusively clarified, there are ongoing discussions ...
Joachim Dissemond   +3 more
wiley   +1 more source

Providing Adapted Care for Patients with Immune-mediated Mucous Membrane Conditions. [PDF]

open access: yes, 2015
PosterBackground: Immune-mediated diseases frequently manifest in the oral mucosa, which may be the first clinical sign for many patients. Some of these diseases present in ways that are pathognomonic (specific) for the condition; however, others have ...
Bailey, Scheri   +2 more
core  

Bullous pemphigoid

open access: yesIndian Journal of Dermatology, Venereology, and Leprology, 2011
Bullous pemphigoid (BP) is a relatively common autoimmune vesicobullous disease encountered in India. It is a subepidermal bullous disorder most commonly seen in the elderly and manifests as tense blisters on urticarial base, predominantly over flexures, and is associated with pruritus.
Sujay, Khandpur, Parul, Verma
openaire   +2 more sources

Paraneoplastic pemphigus: insight into the autoimmune pathogenesis, clinical features and therapy [PDF]

open access: yes, 2017
Paraneoplastic pemphigus is a rare autoimmune skin disease that is always associated with a neoplasm. Usually, oral, skin, and mucosal lesions are the earliest manifestations shown by paraneoplastic pemphigus patients.
Andrea Ciofalo   +21 more
core   +2 more sources

Paraneoplastic bullous pemphigoid – A sign of clear cell renal carcinoma

open access: yesUrology Case Reports, 2020
Paraneoplastic bullous pemphigoid is a rare paraneoplastic syndrome. Rash is pruritic, with erythematous eruption of large subepidermal bullae over skin and often mucosal surfaces.
Stuart R. Jackson   +5 more
doaj   +1 more source

Significance of epitope spreading in the pathogenesis of pemphigus vulgaris and foliaceus [PDF]

open access: yes, 2008
Os pênfigos são dermatoses bolhosas auto-imunes, em que há a produção de auto-anticorpos direcionados contra moléculas de adesão dos epitélios, levando à perda da coesão celular.
AOKI, Valéria   +5 more
core   +2 more sources

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