Results 101 to 110 of about 16,214 (225)
Introduction: Based on recent research, cytokines particularly IL-1α, IL-10, and INF-α might play a role in the pathogenesis of pemphigus vulgaris. Some autoimmune diseases have been successfully treated with the use of antibodies against cytokines.
Faezeh Khozeimeh, Majid Jafari
doaj
Is It Time to Reconsider Rituximab Dosing Regimens for Pemphigus Vulgaris?
Rituximab is currently approved for patients affected by moderate-to-severe pemphigus vulgaris, a severe autoimmune blistering skin disease that can be life-threatening.
Christian Ciolfi +2 more
doaj +1 more source
Background: Pemphigus vulgaris is an autoimmune bullous dermatosis for which high-dose glucocorticoid (GC) therapy is the first-line treatment. However, the use of supraphysiological GC doses may lead to the development of hypercortisolism symptoms ...
Nataliia A. Budul +6 more
doaj +1 more source
Vascular cognitive impairment in Pemphigus vulgaris: a case report
Pemphigus vulgaris is a systemic auto-immune medical condition that mainly manifests with changes in skin and vasculopathy. This is a case report of a 69-year-old male with confirmed histopathologic diagnosis of Pemphigus vulgaris presenting ulterior ...
José Ibiapina Siqueira- Neto +6 more
doaj +1 more source
Triamcinolone acetonide for rare ocular manifestations of pemphigus vulgaris: a case report
N Kozeis1, S Tyradellis1, E Dragiotis1, H Eleftheriadis21Department of Ophthalmology, Hippokration Hospital of Thessaloniki, Greece; 2Southend Hospital NHS Trusts, Westcliff-on-Sea, Essex, UKAbstract: We present an interesting case of pemphigus vulgaris ...
N Kozeis +3 more
doaj
Conjoint analysis of methylation, transcriptomic, and proteomic profiles in pemphigus vulgaris
Background The underlying pathogenesis of pemphigus vulgaris, an autoimmune skin disorder, remains incompletely understood. An integrative analysis comprising DNA methylation, mRNA expression, and proteomic data in patients with pemphigus vulgaris was ...
Xiaojia Luo +6 more
doaj +1 more source
Dupilumab for bullous pemphigoid with intractable pruritus [PDF]
Bullous pemphigoid (BP) is an autoimmune blistering disorder that predominantly affects the elderly. Treatment regimens typically include topical and systemic immunosuppressive medications.
Eichenfield, Dawn Z +2 more
core
The discovery of the role of Bruton’s Tyrosine Kinase (BTK) in inflammation and autoimmunity has recently led to the development of BTK inhibitors for the treatment of autoimmune diseases, including pemphigus vulgaris.
Christian Ciolfi +5 more
doaj
Indirect immunofluorescence (IIF) has been used to identify and measure autoantibody levels in pemphigus vulgaris but data about relationship between clinical severity of disease and antibody titers by IIF have been conflicting.
H. Mortazavi +2 more
doaj

