Results 191 to 200 of about 44,017 (216)

On Inclusion of Covariates in Model Based Dose Finding Clinical Trial Designs. [PDF]

Stat Med
Ollier A, Mozgunov P.
europepmc   +1 more source

Machine Learning for Designing Perovskites and Perovskite‐Inspired Solar Materials: Emerging Opportunities and Challenges

Advanced Science, EarlyView.
This review offers a comprehensive comparison between perovskites and perovskite‐inspired materials (PIMs), focusing on their crystal structures, electronic properties, and chemical compositions. It evaluates the applicability of machine learning (ML) descriptors and models across both material classes.
Yangfan Zhang, Yiming Xia, Ali Shakiba, Hongrui Zhang, Xiaojing Hao, Priyank V. Kumar, Mahesh P. Suryawanshi   +6 more
wiley   +1 more source

Leveraging complex network features improves vaccine stance classification. [PDF]

Sci Rep
Durazzi F, Barbieri N, Faccin M, Gore D, Remondini D.   +4 more
europepmc   +1 more source

Evolutionary Assembly and Future Design of Gibberellin Signaling

Advanced Science, EarlyView.
ABSTRACT Gibberellin (GA) signaling is widely regarded as a canonical hormone‐controlled growth pathway, yet accumulating evidence suggests that it emerged through stepwise evolutionary assembly rather than as a pre‐formed regulatory system. Here, we revisit the origin and diversification of the GA pathway from an evolutionary perspective.
Weishu Fan, Xihan Chen, Dan Li, Xiuhua Gao, Xiangdong Fu   +4 more
wiley   +1 more source

Generalized Additive Modeling of Ecological Data With mgcv: New Adequacy Assessment Tools. [PDF]

Ecol Evol
Mainguy J, McInerney R, Millar RB, Valiquette E, Bélanger M, Moral RA.   +5 more
europepmc   +1 more source

SDS‐CRISPR for Single‐Nucleotide Variant Detection

Advanced Science, EarlyView.
Structure‐disruption‐sensitive CRISPR (SDS‐CRISPR) converts structural instability into single‐nucleotide precision, thereby overcoming mismatch tolerance in canonical Cas12a and enabling versatile diagnostics across DNA, RNA, and microRNA targets. When applied to rapid IDH1 mutation detection for glioma genotyping and integrated with lateral‐flow ...
Xin Guan, Chong Guo, Jiongyu Zhang, Rui Yang, Yerramsetti Ramachandra, Chengyu Hou, Minjie Pei, Shuo Zhang, Kurt T. Schalper, Xingye Liu, Qian Wu, Ketan R. Bulsara, Changchun Liu   +12 more
wiley   +1 more source

Topology optimization of wheel spoke cavities for lightweight design under bending fatigue and impact load cases. [PDF]

Sci Rep
Zhang G, Cui X, Zang Y, Zhou Y, Lu J, Li Z, Yang H, Wang J, Ye Z, Li R, Zhou L.   +10 more
europepmc   +1 more source

A FAP‐Targeted SMDC Platform Enables Synergistic Radionuclide–Chemotherapy with PET‐Guided Evaluation

Advanced Science, EarlyView.
A fibroblast activation protein (FAP)‐targeted small molecule–drug conjugate (SMDC) platform is developed to integrate PET imaging with synergistic radionuclide–chemotherapy. Linker chemistry governs stability, exposure, and tolerability, with the VC linker providing superior in vivo performance.
Ruitao Yang, Hongxin Li, Zexin Xu, Baocheng Chen, Ningjie Li, Yuhua Zhong, Kongzhen Hu   +6 more
wiley   +1 more source

Predicting Adverse Events in Blunt Chest Trauma: A Novel Nomogram Integrating Vitals, Hemogram, and Comorbidities. [PDF]

Kaohsiung J Med Sci
Huang CL, Hsieh HM, Kor CT, Chou MC, Chang PC, Chang TW, Chen CW.   +6 more
europepmc   +1 more source

Organic Thin‐Film Transistors for Neuromorphic Computing

Advanced Electronic Materials, EarlyView.
Organic thin‐film transistors (OTFTs) are reviewed for neuromorphic computing applications, highlighting their power‐efficient, and biological time‐scale operation. This article surveys OFET and OECT devices, compares them with memristors and CMOS, analyzes how fabrication parameters shape spike‐based metrics, proposes standardized characterization ...
Luke McCarthy, Mohan V. Jacob, Mostafa Rahimi Azghadi   +2 more
wiley   +1 more source