Results 31 to 40 of about 44,017 (216)
DINA Model with Entropy Penalization
Mathematics, 2023 The cognitive diagnosis model (CDM) is an effective statistical tool for extracting the discrete attributes of individuals based on their responses to diagnostic tests.
Juntao Wang, Yuan Li
doaj +1 more source
, 2019 We develop a volume penalization method for inhomogeneous Neumann boundary conditions, generalizing the flux-based volume penalization method for homogeneous Neumann boundary condition proposed by Kadoch et al. [J. Comput. Phys. 231 (2012) 4365].
90836 +7 more
core +3 more sources
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Generalizing Gain Penalization for Feature Selection in Tree-Based Models
IEEE Access, 2020 We develop a new approach for feature selection via gain penalization in tree-based models. First, we show that previous methods do not perform sufficient regularization and often exhibit sub-optimal out-of-sample performance, especially when correlated ...
Bruna Wundervald +2 more
doaj +1 more source
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Analysis of genome-wide association studies with multiple outcomes using penalization. [PDF]
PLoS ONE, 2012 Genome-wide association studies have been extensively conducted, searching for markers for biologically meaningful outcomes and phenotypes. Penalization methods have been adopted in the analysis of the joint effects of a large number of SNPs (single ...
Jin Liu, Jian Huang, Shuangge Ma
doaj +1 more source
Microscopic Model of Intermediate Phase in Flexible to Rigid Transition
Frontiers in Physics, 2021 We introduce a lattice gas model with a modified Hamiltonian considering different energy for cycles of connected atoms. The system can be interpreted as a chalcogenide glass with pollutants forming floppy and rigid structures.
Aldo Sayeg Pasos-Trejo +1 more
doaj +1 more source
Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
Fluids, 2021 This work extends the characteristic-based volume penalization method, originally developed and demonstrated for compressible subsonic viscous flows in (J. Comput. Phys.
Nurlybek Kasimov +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source