Results 171 to 180 of about 6,450 (280)

Distinct Prescription Patterns Emerge Years Before ALS Diagnosis: A Nationwide Registry‐Based Study

Annals of Neurology, Volume 99, Issue 6, Page 1516-1525, June 2026.
Objective The prodromal phase of amyotrophic lateral sclerosis (ALS) is poorly defined. We aimed to characterize prescription drug use patterns in the pre‐diagnostic period by analyzing nationwide prescription data to identify the earliest divergence between individuals who developed ALS and matched healthy controls.
Magne Haugland Solheim, Trond Riise, Marianna Cortese, Ola Nakken, Ole‐Bjørn Tysnes, Jannicke Igland, Kjetil Bjornevik   +6 more
wiley   +1 more source

Nonparametric Density Estimation for Data Scattered on Irregular Spatial Domains: A Likelihood-Based Approach Using Bivariate Penalized Spline Smoothing. [PDF]

J Nonparametr Stat
Das K, Yu S, Wang G, Wang L.
europepmc   +1 more source

The DeepJoint Algorithm: An Innovative Approach for Studying the Longitudinal Evolution of Quantitative Mammographic Density and Its Association With Screen‐Detected Breast Cancer Risk

Biometrical Journal, Volume 68, Issue 3, June 2026.
ABSTRACT High mammographic density is a well‐known risk factor for breast cancer and reduces the sensitivity of mammography‐based screening. While automated machine and deep learning‐based methods provide more consistent and precise measurements compared to subjective Breast Imaging Reporting and Data System (BI‐RADS) assessments, they often fail to ...
Manel Rakez, Julien Guillaumin, Aurelien Chick, Gaelle Coureau, Foucauld Chamming's, Pierre Fillard, Brice Amadeo, Virginie Rondeau   +7 more
wiley   +1 more source

HPV‐Adjusted Feature Screening With FDR Control in Head and Neck Cancer

Biometrical Journal, Volume 68, Issue 3, June 2026.
ABSTRACT Human papillomavirus (HPV) is a well‐established prognostic factor in head and neck (HN) cancer, with HPV‐positive patients exhibiting markedly better survival outcomes compared to their HPV‐negative counterparts. While advances in (cancer) genomics have been pivotal to precision medicine, existing gene screening methods for identifying ...
Atika Farzana Urmi, Chenlu Ke, Dipankar Bandyopadhyay   +2 more
wiley   +1 more source

Simultaneous Confidence Bands for Penalized Spline Estimators

In this paper we construct simultaneous confidence bands for a smooth curve using penalized spline estimators. We consider three types of estimation methods: (i) as a standard (fixed effect) nonparametric model, (ii) using the mixed model framework with ...
Thomas Kneib, Gerda Claeskens, Tatyana Krivobokova   +2 more
core  

Vocal Phenology of Forest Tinamous Along a Latitudinal Gradient: Effects of Daylength and Precipitation

Ecology and Evolution, Volume 16, Issue 6, June 2026.
Based on an analysis of eBird records, this study finds that the vocal patterns of tropical forest tinamous are primarily influenced by changes in daylength, with a secondary effect of precipitation. Birds sang more when days were longer or shorter than 12 h and during drier periods, especially in wetter regions.
Oscar Laverde‐R., Santiago Muñoz Bolaños, Gustavo A. Londoño, Christian Devenish   +3 more
wiley   +1 more source

Using Landsat Satellite Imagery to Investigate Spatial and Temporal Variation in Life History Traits in a Long‐Term Study Population of Superb Fairy‐Wrens Malurus cyaneus

Ecology and Evolution, Volume 16, Issue 6, June 2026.
We used 27 years of data from an insectivorous passerine in southeastern Australia, the superb fairy‐wren Malurus cyaneus, to assess how climate variation influences vegetation productivity and, indirectly, reproduction and survival via potential trophic interactions.
Richard S. Turner, Ophélie J. D. Lasne, Lei Lv, Helen L. Osmond, Andrew Cockburn, Loeske E. B. Kruuk, Kara N. Youngentob   +6 more
wiley   +1 more source

Exercise type, dose and mental health outcomes in youth: Which types and doses are sufficient?

General Psychiatry, Volume 39, Issue 3, June 2026.
ABSTRACT Background Although experimental evidence supports links between exercise and certain mental health indicators, epidemiological research has focused primarily on the dose–response effect of a single type of exercise, overlooking potential differences across exercise types in their associations with overall and specific mental health outcomes ...
Huagen Wang, Yisheng Aku, Shicun Xu, Zhanbing Ren, Yingjie Zhang, Runsen Chen, Jing An   +6 more
wiley   +1 more source

ComBat‐Predict Enhances Generalizability of Neuroimaging Models to New Sites

Human Brain Mapping, Volume 47, Issue 8, June 1, 2026.
ComBat‐Predict effectively harmonizes data from a new site, improving the applicability of normative models to private data. ComBat‐Predict is available for R in the ComBatFamily package. ABSTRACT Neuroimaging is vital in quantifying brain atrophy due to typical aging and due to neurodegenerative diseases.
Yao Xin, Margaret Gardner, Nicholas J. Tustison, Philip Cook, James Gee, Andreana Benitez, Jens H. Jensen, Alzheimer's Disease Neuroimaging Initiative, Lifespan Brain Chart Consortium, Richard Bethlehem, Jakob Seidlitz, Aaron F. Alexander‐Bloch, Andrew A. Chen   +12 more
wiley   +1 more source

First-passage-based boundary estimation in functional data. [PDF]

PLoS One
Kuzu AT, Celik N.
europepmc   +1 more source