Results 41 to 50 of about 22,664 (309)

Performance of pre-hospital evaluations in ruling out invasive chest stab wounds

open access: yesScandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 2020
Background Some guidelines advocate for managing patients with penetrating thoracic wounds in trauma centres with cardiothoracic surgery. This systematic approach is questionable. Only 15% of these patients require surgery.
Pascal Augustin   +7 more
doaj   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

open access: yesFEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori   +8 more
wiley   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

An unusual case of penetrating head injury in a child

open access: yesJournal of Emergencies, Trauma and Shock, 2010
Penetrating head injuries can be the result of numerous intentional or unintentional events, including missile wounds, stab wounds, and motor vehicle or occupational accidents (nails, screw-drivers).
Karim Tanweer, Topno Margaret
doaj  

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

open access: yesAging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey   +12 more
wiley   +1 more source

Consideration of penetrating abdominal trauma, a retrospective study.

open access: yesAlbanian Journal of Trauma and Emergency Surgery, 2017
Background; Nowadays penetrating trauma is increasing because of the growth of violence in our society. The penetrating injury (PI) constitute about 6% of the hospitalized cases and 10% of visits to the emergency department (ED), they are calculated to ...
Agron Dogjani   +4 more
doaj   +1 more source

NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao   +10 more
wiley   +1 more source

Unusual weapon of a murder case- A case of fatal penetrating chest trauma

open access: yesForensic Science International: Reports
To solve complex forensic cases, medico-legal issues such as cause of death, manner of death, weapon used, postmortem interval, and volitional activity must be resolved.
U. Mayorathan, M. Sriluxayini
doaj   +1 more source

Penetrating gunshot wounds to the penis: a case report of combat patient injured in the war in Ukraine [PDF]

open access: gold, 2023
Sergiy Golovko   +7 more
openalex   +1 more source

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