Results 61 to 70 of about 726,826 (328)

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

open access: yesMolecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova   +18 more
wiley   +1 more source

Dorsal vertebro-medullary stab wound: Two cases from Niamey National Hospital and review of literature

open access: yesInterdisciplinary Neurosurgery, 2023
Background: Stab wounds are rare, accounting for around 25 % of all spinal cord injuries. They are the most frequent cause of penetrating wounds and occur mainly after an assault or suicide attempt.
Ibrahim Issa Assoumane   +6 more
doaj  

Огнестрельные проникающие ранения позвоночника и спинного мозга [PDF]

open access: yes, 2012
Дослідження присвячене особливостям найбільш важкого виду спінальних вогнепальних ушкоджень - проникаючим пораненням.Research is devoted to the peculiarities of the most severe form of spinal gunshot wounds - a penetrating ...
Максимов, С.А.
core  

Operative and nonoperative management for renal trauma. Comparison of outcomes. A systematic review and meta-analysis [PDF]

open access: yes, 2017
INTRODUCTION: Preservation of kidney and renal function is the goal of nonoperative management (NOM) of renal trauma (RT). The advantages of NOM for minor blunt RT have already been clearly described, but its value for major blunt and penetrating RT is ...
Brachini, Gioia   +6 more
core   +1 more source

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

open access: yesMolecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma   +9 more
wiley   +1 more source

TRPM8 levels determine tumor vulnerability to channel agonists

open access: yesMolecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo   +18 more
wiley   +1 more source

An unusual case of penetrating head injury in a child

open access: yesJournal of Emergencies, Trauma and Shock, 2010
Penetrating head injuries can be the result of numerous intentional or unintentional events, including missile wounds, stab wounds, and motor vehicle or occupational accidents (nails, screw-drivers).
Karim Tanweer, Topno Margaret
doaj  

APPENDICULAR CARCINOID IN A VICTIM WITH SIMULTANEOUS CHEST AND ABDOMEN TRAUMA

open access: yesНеотложная медицинская помощь, 2017
The article reports a clinical case of surgical therapy of a patient with simultaneous chest and abdomen trauma and carcinoid of the appendix.
E. V. Tatarinova, G. A. Nefedova
doaj   +1 more source

A retrospective study on 195 horses with contaminated and infected synovial cavities [PDF]

open access: yes, 2009
This study analyzes the clinical aspects of contaminated and infected synovial cavities in horses and evaluates their prognosis after treatment. The medical records of 195 affected horses referred between June 1999 and July 2004 were reviewed. Twenty-six
Dewulf, Jeroen   +5 more
core   +1 more source

Loss of primary cilia promotes EphA2‐mediated endothelial‐to‐mesenchymal transition in the ovarian tumor microenvironment

open access: yesMolecular Oncology, EarlyView.
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho   +11 more
wiley   +1 more source

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