Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Comparison of suture anchor penetration rate between navigation-assisted and traditional shoulder arthroscopic capsulolabral repair. [PDF]
PLoS One, 2022 Pan HK, Liu CW, Pan RY.
europepmc +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Rate dependent penetration of dry sand [PDF]
AIP Conference Proceedings, 2020 S. Bless +3 more
openaire +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Changes in the Penetration Rate of Biosimilar Infliximab Within Japan Using a Japanese Claims Database. [PDF]
Clinicoecon Outcomes Res, 2021 Matsumoto T +5 more
europepmc +1 more source
Desiccation of a clay film: Cracking versus peeling
, 2008 Cracking and peeling of a layer of clay on desiccation has been simulated using a spring model. A vertical section through the layer with finite thickness is represented by a rectangular array of nodes connected by linear springs on a square lattice. The
Blaudeck, Peter +5 more
core +1 more source
A Study on Factors Affecting Airborne LiDAR Penetration
Terrestrial, Atmospheric and Oceanic Sciences, 2015 This study uses data from different periods, areas and parameters of airborne LiDAR (light detection and ranging) surveys to understand the factors that influence airborne LiDAR penetration rate.
Wei-Chen Hsu +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
The Effect of Injection-Valve Opening Pressure on Spray-Tip Penetration [PDF]
The effect of various injection-valve opening pressures on the spray-tip penetration was determined for several injection pressure. A common-rail fuel injection system was used.
Marsh, E T, Rothrock, A M
core +1 more source