Results 71 to 80 of about 76,342 (254)

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Penetration detection and vital-information recognition for drilling rescue with ultrawideband radar in underground sheltered space

Alexandria Engineering Journal
Extensive studies have been reported on the application of ultrawideband (UWB) radar in rescue operations in the case of accidents. However, the identification of vital information in underground shelter spaces should be further improved to ensure ...
Guobin Cai, Xuezhao Zheng, Jun Guo, Hu Wen, Wenjing Gao   +4 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Advancing Defect Detection in Laser Welding: A Machine Learning Approach Based on Spatter Feature Analysis

Sensors
Full-penetration laser welding (FPLW) is increasingly adopted in manufacturing pipelines, yet its industrial scalability is constrained by in-process defect formation, particularly incomplete penetration.
Gleb Solovev, Evgenii Klokov, Dmitrii Krasnov, Mikhail Sokolov   +3 more
doaj   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Assessment of Penetration Depth of Silver Diamine Fluoride in Synthetic Dental Minerals

Inorganics
Dental caries is a prevalent global health issue characterized by the progressive demineralization of dental tissues, which occurs when the balance between demineralization and remineralization processes is disrupted at the tooth level.
Daniella Battaglia, Brunna da Silva Nobrega Souza, Ana Carla B. C. J. Fernandes, Rodrigo França   +3 more
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Intelligent Recognition of Road Internal Void Using Ground-Penetrating Radar

Applied Sciences
Internal road voids can lead to decreased load-bearing capacity, which may result in sudden road collapse, posing threats to traffic safety. Three-dimensional ground-penetrating radar (3D GPR) detects internal road structures by transmitting high-frequency electromagnetic waves into the ground and receiving reflected waves.
Qian Kan, Xing Liu, Anxin Meng, Li Yu
openaire   +2 more sources