Results 151 to 160 of about 213,287 (300)

Estimation of Deep Penetration Resistance with Spherical Specific Cavitation Energy

open access: yes, 2010
A simple model is suggested for deep penetration resistance of rigid, axially-symmetric, nose-pointed projectiles penetrating ductile metal targets.
Rami Masri
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

On the critical thickness of ceramic to shatter WC-Co bullet cores [PDF]

open access: yes, 2011
In this paper, the 7.62 mm x 51 mm FFV round consisting of a tungsten carbide core (1550 HV) and copper gilding jacket was fired at silicon nitride, titanium diboride, tungsten carbide and silicon carbide ceramics. Of particular interest is the thickness
Hazell, Paul J., Roberson, Colin J.
core  

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

The relationships between penetration resistance and soil properties

open access: yes, 1999
Bu çalışmanın amacı, dört farklı toprağın penetrasyon direnci ile ölçülen bazı özellikleri arasındaki ilişkileri ortaya koyarak, penetrasyon direncinin tahminini sağlayan regresyon denklemlerini geliştirmektir.
Şeker, Cevdet
core  

Time-dependent changes in distribution patterns of soil penetration resistance in a rangeland under overgrazing [PDF]

open access: yes, 2008
Soil penetration resistance as an indication of soil compaction affects on soil infiltration and runoff. Overgrazed rangelands are under severe erosion risk because of compaction. The objective of this study was to determine changes in soil penetration
Aksakal, E. L., Özgül, M., Öztaş, T.
core  

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

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