Results 31 to 40 of about 6,518 (178)

Chlorogenic Acid: A Promising Strategy for Milk Preservation by Inhibiting Staphylococcus aureus Growth and Biofilm Formation

Foods
Chlorogenic acid (CGA), a polyhydroxy phenolic acid, has been extensively studied for its antimicrobial properties. Staphylococcus aureus (S. aureus) threatens food safety by forming biofilms.
Xiaoyan Yu, Yufang Li, Xue Yang, Jinze He, Wenhuan Tang, Yunmei Chai, Zuyan Duan, Wenjie Li, Dan Zhao, Xuefeng Wang, Aixiang Huang, Hong Li, Yanan Shi   +12 more
doaj   +1 more source

Cell wall peptidoglycan in Mycobacterium tuberculosis: An Achilles’ heel for the TB-causing pathogen [PDF]

, 2019
Tuberculosis (TB), caused by the intracellular pathogen Mycobacterium tuberculosis, remains one of the leading causes of mortality across the world. There is an urgent requirement to build a robust arsenal of effective antimicrobials, targeting novel ...
Bhakta, S, Healy, J, Keep, NH, Maitra, A, Martin, LT, Munshi, TK, Vollmer, W   +6 more
core   +2 more sources

Alteration of the catalytic efficiency of penicillin amidase from Escherichia coli [PDF]

Applied and Environmental Microbiology, 1989
Ampicillin and cephalexin are beta-lactam antibiotics that are synthesized by the condensation of D-(-)-alpha-aminophenylacetic acid with 6-aminopenicillanic acid or 7-aminodeacetoxycephalosporanic acid, respectively. The rates at which the penicillin amidase of Escherichia coli catalyzes these reactions are too low to be of practical use.
L J, Forney, D C, Wong
openaire   +2 more sources

Genome‐Wide In Silico Analysis of the Type VI Secretion System (T6SS) Within the Morganella Genus

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
▪ Species‐specific T6SS patterns among Morganella genus (M. morganii and M. sibonii). ▪ Only one‐third of M. morganii isolates haboured a T6SS. ▪ All M. sibonii possess four T6SS clusters. ▪ M. sibonii exhibited a wide diversity of effectors compared to M. morganii.
Mathilde Duque, Aymeric Jacquemin, Delphine Girlich, Rémy A. Bonnin, Laurent Dortet   +4 more
wiley   +1 more source

Outer Membrane Vesicles Mediate the Secretion and Nuclear Trafficking of a Bacterial Nucleomodulin

Journal of Extracellular Vesicles, Volume 15, Issue 5, May 2026.
(A) We propose that Helicobacter pylori secretes a nucleomodulin, Tumour Necrosis Factor‐α‐inducing protein (Tipα), predominantly via extracellular vesicles (EVs), also known as outer membrane vesicles, rather than as free protein. (B) EVs carrying Tipα enter eukaryotic cells by endocytosis and independently of surface‐expressed nucleolin, then traffic
Jack K. Emery, Variya Nemidkanam, Nina Colon, Kate R. J. Friesen, Lena H. M. Le, Angus R. Cramond, Maxine Yap, Mônica S. Barbosa, Georgie Wray‐McCann, David J. McGee, Natalia Castaño‐Rodríguez, Dongmei Tong, Caroline Skene, Laurent Terradot, Richard L. Ferrero   +14 more
wiley   +1 more source

Studies on microbial penicillin amidase (IV). The production of penicillin amidase from a partially constitutive mutant of Bacillus megaterium.

The Journal of General and Applied Microbiology, 1982
A partially constitutive mutant strain for penicillin amidase production was derived from the parent strain Bacillus megaterium ATCC 14945 by treatment with UV light. The mutant (B. megaterium KFCC 10029) showed two phenotypical changes in the mode of penicillim amidase production and in the size of cell chains.
HYEUNG-JIN SON, TAE-ICK MHEEN, BAIK-LIN SEONG, MOON H. HAN   +3 more
openaire   +2 more sources

Purification and Properties of Penicillin Amidase from Bacillus megaterium [PDF]

Journal of Bacteriology, 1967
A penicillin amidase, obtained from the exogenous medium of a Bacillus megaterium culture, was purified approximately 96-fold by means of two cycles of adsorption on, and elution from, Celite, followed by a further fractionation on carboxymethylcellulose.
C, Chiang, R E, Bennett
openaire   +2 more sources

Cell wall elongation mode in Gram-negative bacteria is determined by peptidoglycan architecture [PDF]

, 2013
Cellular integrity and morphology of most bacteria is maintained by cell wall peptidoglycan, the target of antibiotics essential in modern healthcare.
Cadby, A., Foster, S.J., Hobbs, J.K., Hurd, A.F., Turner, R.D.   +4 more
core   +1 more source

Penicillin Amidase from Coliforms: its Extraction and some Characteristics [PDF]

Nature, 1964
IT is known that many fungi and some bacteria produce penicillin-splitting amidases or acylases1,2. With the exception of the amidase from Streptomyces lavendulaedescribed by Batchelor, Chain, Richards and Rolinson3, few details have been published about these enzymes.
R J, HOLT, G T, STEWART
openaire   +2 more sources

Nanotherapeutic Macrophage‐Neuro Reprogramming Through Immunometabolic Crosstalk Mitigates Sepsis‐Induced Lung Injury and Neurologic Damage

Advanced Science, Volume 13, Issue 24, 27 April 2026.
SJNPs co‐deliver JHU083 and spermine to reprogram macrophage–neuron immunometabolic crosstalk in sepsis. By suppressing pro‐inflammatory M1 polarization and promoting NGF‐mediated neurotrophic signaling, SJNPs preserve pulmonary neuronal integrity, alleviate lung injury, and improve survival in murine sepsis models.
Wenhui Wang, Yongrui Hai, Xintong Lu, Ye Chen, Bingjie Zhang, Renming Fan, Jiarui Dou, Jiaxin Yan, Shuo Fu, Wen Zhang, Junke Song, Gaofei Wei   +11 more
wiley   +1 more source