Soft Nanocarriers as Antimicrobial Co‐Delivery Systems to Combat Resistant Infections
Advanced Healthcare Materials, Volume 14, Issue 21, August 19, 2025.Soft nanocarrier‐based co‐delivery systems present a versatile and promising platform for combating antimicrobial resistance (AMR) by enabling spatiotemporally controlled, pathogen‐specific drug release. Their tunable physicochemical properties allow for the co‐encapsulation of synergistic antimicrobial agents, optimization of drug ratios, and surface ...
Anamarija Nikoletic +5 more
wiley +1 more source
Differences of Pathophysiology in Experimental Meningitis Caused by Three Strains of Streptococcus Pneumoniae [PDF]
, 2017 Differences in cytochemical and pathophysiologic abnormalities in experimental meningitis caused by pneumococcal strains A, B, and C were determined. Strain C produced the most severe abnormalities of cerebrospinal fluid (CSF) concentrations of lactate ...
Borschberg, Urs +5 more
core
Combined Forces Against Bacteria: Phages and Antibiotics
Health Science Reports, Volume 8, Issue 7, July 2025.ABSTRACT Background and Aim It is now known that bacteria are highly interactive and exhibit a range of complex cooperative behaviors, including conjugal plasmid transfer, toxins, swarming, drug resistance, toxin production, biofilm development, and other virulence traits.
Shima Afrasiabi +3 more
wiley +1 more source
The role of peptidoglycan in chlamydial cell division: towards resolving the chlamydial anomaly [PDF]
, 2017 Chlamydiales are obligate intracellular bacteria including some important pathogens causing trachoma, genital tract infections and pneumonia, among others. They share an atypical division mechanism, which is independent of an FtsZ homologue.
Gerdes, Kenn +3 more
core
Bacteriophage endolysins as a response to emerging foodborne pathogens [PDF]
, 2012 Continuous reports on foodborne outbreaks and increasing prevalence of antibiotic-resistant bacteria call for the development of novel preservation techniques that assure the safety of food products.
Azeredo, Joana +3 more
core +1 more source
Phage and Endolysin Therapy Against Antibiotics Resistant Bacteria: From Bench to Bedside
MedComm, Volume 6, Issue 7, July 2025.Synergistic effects of combining bacteriophages and antibiotics in antimicrobial therapy. The diagram illustrates key advantages of phage‐antibiotic synergy, including increased treatment effectiveness, reduced minimum inhibitory concentration (MIC) for drug‐resistant strains, enhanced biofilm eradication, and inhibition of resistant bacteria ...
Majid Taati Moghadam +5 more
wiley +1 more source
A self-immolative linker that releases thiols detects penicillin amidase and nitroreductase with high sensitivity <i>via</i> absorption spectroscopy. [PDF]
Chem Commun (Camb), 2022 Espinoza EM +13 more
europepmc +1 more source
LytR-CpsA-Psr proteins in Staphylococcus aureus display partial functional redundancy and the deletion of all three severely impairs septum placement and cell separation [PDF]
, 2017 Staphylococcus aureus contains three members of the LytR-CpsA-Psr (LCP) family of membrane proteins: MsrR, SA0908 and SA2103. The characterization of single-, double- and triple-deletion mutants revealed distinct phenotypes for each of the three proteins.
Berger-Bächi, Brigitte +8 more
core
Specificity and Mechanism of Mandelamide Hydrolase Catalysis [PDF]
, 2017 The best-studied amidase signature (AS) enzyme is probably fatty acid amide hydrolase (FAAH). Closely related to FAAH is mandelamide hydrolase (MAH), whose substrate specificity and mechanism of catalysis are described in this paper.
Adediran, S. A. +5 more
core +1 more source
Penicillin amidase from Proteus rettgeri.
Acta biochimica Polonica, 1982 1. Penicillin amidase from Proteus rettgeri was purified 580-fold by a four-step chromatographic procedure. Titration with phenylmethanesulphonyl fluoride showed that the purified preparation contains 53% of the enzyme. 2. The molecular weight of the amidase was found to be 65.000.
M, Robak, A, Szewczuk
openaire +1 more source