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Disposition of penicillin G after administration of benzathine penicillin G, or a combination of benzathine penicillin G and procaine penicillin G in cattle

American Journal of Veterinary Research, 1994
Summary Plasma concentration of penicillin G was evaluated in beef steers after administration of either a combination of benzathine penicillin G and procaine penicillin G in a 1:1 mixture at a dosage of 9,000 U/kg of body weight, im (n = 5), 24,000 U/kg, im (n = 5), or 8,800 U/kg, sc (n = 5), or benzathine penicillin G alone at a dosage of 12,000 U/kg,
M G, Papich   +7 more
openaire   +2 more sources

Anaphylaxis to Benzathine Penicillin G

Pediatric Asthma, Allergy & Immunology, 2000
We report on two military trainees who experienced anaphylaxis following an injection of benzathine penicillin G (BPG). A total of 9203 trainees received a prophylactic dose of BPG over a 6-month period for an incidence rate of 0.022%. One of the trainees experienced biphasic or recurrent anaphylaxis.
Diane C. Napoli, Teresa A. Neeno
openaire   +1 more source

Lidocaine as a diluent for administration of benzathine penicillin G

The Pediatric Infectious Disease Journal, 1998
Benzathine penicillin G is recommended for secondary prophylaxis of rheumatic fever. Its main disadvantage is local pain and discomfort associated with the injection. Lidocaine as a diluent may reduce this discomfort. We compared the administration of benzathine penicillin G with two diluents; sterile water and lidocaine hydrochloride 1% for penicillin
J, Amir   +5 more
openaire   +2 more sources

BENZATHINE PENICILLIN G IN THE PREVENTION OF STREPTOCOCCIC INFECTIONS

Journal of the American Medical Association, 1957
The effectiveness of benzathine penicillin G in preventing streptococcic pharyngitis was determined during an epidemic of this disease among military personnel at an air force base. A single intramuscular injection was given to each of 741 men, representing about 10 % of the exposed population.
A J, MORRIS, C H, RAMMELKAMP
openaire   +2 more sources

IMPROVED LOCAL TOLERANCE TO BENZATHINE PENICILLIN G

Pediatrics, 1958
Four types of penicillin for intramuscular injection were compared for incidence of local reaction: (1) suspension of benzathine penicillin G, 600,000 units in 1 ml; (2) benzathine penicillin G, 600,000 units, with 5 mg of prednisolone, in 1 ml; (3) benzathine penicillin G, 600,000 units, plus aqueous procaine penicillin, 600,000 units, in 2 ml; and (4)
S, KRUGMAN, E V, EBIN
openaire   +2 more sources

BENZATHINE PENICILLIN G

Journal of the American Medical Association, 1954
To the Editor:— In an editorial on page 894 in the Oct. 30, 1954, issue ofThe Journal, I note that a competitive company's benzathine penicillin G is mentioned by brand name in such a way as to imply that no other company supplies this preparation. We believe that, by neglecting to give more than the one brand name, the editorial will serve to promote
openaire   +1 more source

Cerebrospinal fluid levels of benzathine penicillin G in the neonate

The Journal of Pediatrics, 1977
T n E I N C ! D E N C E of congenital syphili s has increased in recent years, 1 prompting renewed interest in the treatment of this entity. One recommended form of therapy is benzathine penicillin G, 100,000 units per kilogram of body weight given in a single intramuscular injection.
M E, Speer   +3 more
openaire   +2 more sources

REACTIONS FROM MULTIPLE INJECTIONS OF BENZATHINE PENICILLIN G

Journal of the American Medical Association, 1957
A comparison was made between two dosage plans for the intramuscular administration of benzathine penicillin G as prophylaxis against rheumatic fever, nephritis, and streptococcic infections in the armed forces. One group of 1,567 men received 600,000 units every four weeks; the other group, of 1,708 men, received 900,000 units every six weeks.
R W, SHERWOOD, C, GRONBECK, F W, DENNY
openaire   +2 more sources

Failure of Penicillin G Benzathine in the Treatment of Neurosyphilis

Archives of Internal Medicine, 1980
• Although penicillin remains highly effective in syphilis, important questions exist regarding the optimal regimen for syphilitic involvement of the nervous system. Progression of neurosyphilis despite 7.2 million units of penicillin G benzathine occurred in the case reported here, with subsequent resolution following high-dose intravenous aqueous ...
B M, Greene, N R, Miller, T E, Bynum
openaire   +3 more sources

Penicillin Concentrations in Serum Following Weekly Injections of Benzathine Penicillin G

Chemotherapy, 2009
Twelve patients with syphilis were treated weekly with injections of 1.44 g (2.4 x 106 IU) of benzathine penicillin G for up to 3 weeks. Almost daily, serum penicillin concentrations were measured by a sensitive microbiological agar cup method. An individual and interindividual variation was found.
H K, Hagdrup   +3 more
openaire   +2 more sources

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