Results 191 to 200 of about 318,787 (256)

A comparison of antibiotic resistance reports in pharmacovigilance databases and conventional surveillance across "One Health". [PDF]

Front Public Health
Mitchell J, Purohit M, Lundquist P, Westerberg C, Stålsby Lundborg C.   +4 more
europepmc   +1 more source

VDAC1 Upregulation Induces Hyperexcitability of Nociceptive Sensory Neurons Via Enhanced Mitochondrial Atp Efflux in Neuropathic Pain

Advanced Science, EarlyView.
The mechanism diagram of VDAC1 mediating neuronal excitability and neuropathic pain. Briefly, VDAC1 is expressed in DRG neurons and is upregulated following CCI‐induced neuropathic pain. This upregulation enhances ATP transport from mitochondria to the cytoplasm in sensory neurons, leading to increased neuronal excitability and pain behavior.
Fengrun Sun, Ning Yu, Liang Yu, Xiaofen Tian, Yujia Ma, Yikuan Xie, Tao Wang, Chao Ma   +7 more
wiley   +1 more source

Antibiotic Prophylaxis and Treatment of Neonatal Group B Streptococcus Disease in the Era of Antimicrobial Resistance. [PDF]

Antibiotics (Basel)
Tzialla C, Salomè S, Mondì V, Salvo V, Berardi A.   +4 more
europepmc   +1 more source

MEOX1 Coordinates Autocrine‐Paracrine Programs via SPHK1/S1P to Promote Lymph Node Metastasis in Ovarian Cancer

Advanced Science, EarlyView.
In ovarian cancer, MEOX1 activates the SPHK1/S1P pathway to promote both tumor progression and tumor–stroma crosstalk. MEOX1‐dependent signaling drives CAF activation, enhances VEGF‐C expression, and stimulates lymphangiogenesis, ultimately facilitating lymph node metastasis.
Jiajia Li, Xiuling Zhi, Qianhan Lin, Yating Sun, Yihua Sun, Zulimire Abudousalamu, Mengyang Xue, Chang Zheng, Xiaotian Li, Liangqing Yao, Mo Chen   +10 more
wiley   +1 more source

Patterns, Associated Factors, and Anatomical Concordance of Nasal and Throat <i>Staphylococcus aureus</i> Carriage Among Community-Dwelling Adults in Germany. [PDF]

Microorganisms
Martens A, Schauer M, Motevalli M, König B.   +3 more
europepmc   +1 more source

In Vitro Antimicrobial Activity of Ceftobiprole and Comparator Agents Against <i>Streptococcus pneumoniae</i> Responsible for Lower Respiratory Tract Infections in the United States (2016-2020), Including Resistant Subsets and Select Serotypes. [PDF]

Antibiotics (Basel)
Sader HS, Castanheira M, Jones ME, Mendes RE.   +3 more
europepmc   +1 more source

Nacubactam: a review on mechanistic insights and therapeutic promise for combating β-lactam resistance among multidrug-resistant Gram-negative pathogens. [PDF]

Ann Med Surg (Lond)
Kumar D, Kaur N, Surender, Aman S, Bibi A.   +4 more
europepmc   +1 more source

Antibiotic-resistance mutations in penicillin-binding protein 2 from the ceftriaxone-resistant Neisseria gonorrhoeae strain H041 strike a delicate balance between increasing resistance and maintaining transpeptidase activity. [PDF]

PLoS Pathog
Bivins MM, Tomberg J, Bagshaw M, Singh A, Bala S, Davies C, Nicholas RA.   +6 more
europepmc   +1 more source