Results 281 to 290 of about 4,016,959 (341)

Penicillin-resistant pneumococcus

Irish Journal of Medical Science, 1988
Penicillin resistant pneumococci are now described world wide, with increasing recognition of the clinical implications of infection with these strains and the laboratory methods required for their identification. In presenting such a case, we suggest thatin vitro sensitivity testing with oxacillin discs affords the best method for detection of ...
G D, Corcoran, T F, Buckley, C, Connor, L, Clancy, C T, Keane   +4 more
openaire   +2 more sources

Novel and Improved Crystal Structures of Haemophilus influenzae, E. coli and P. aeruginosa Penicillin-Binding-Protein 3 (PBP3) and N. gonorrhoeae PBP2: Towards a Better Understanding of β-Lactam Target-Mediated Resistance.

Journal of Molecular Biology, 2019
Even with the emergence of antibiotic resistance, penicillin and the wider family of beta-lactams have remained the single most important family of antibiotics.
D. Bellini, L. Koekemoer, H. Newman, C. Dowson   +3 more
semanticscholar   +1 more source

Evaluation and Management of Penicillin Allergy: A Review

Journal of the American Medical Association (JAMA), 2019
Importance &bgr;-Lactam antibiotics are among the safest and most effective antibiotics. Many patients report allergies to these drugs that limit their use, resulting in the use of broad-spectrum antibiotics that increase the risk for antimicrobial ...
E. Shenoy, E. Macy, Theresa A. Rowe, K. Blumenthal   +3 more
semanticscholar   +1 more source

Penicillin-resistant pneumococci

Drugs of Today, 1998
Penicillin-resistant pneumococci are of concern in respiratory tract infections. Currently, nearly all of the "penicillin resistance" to Streptococcus pneumoniae is relative resistance which indicates decreased antibiotic activity in terms of the MIC, but these isolates are still susceptible to sensitive antibiotics given in the usual/high doses.
openaire   +4 more sources

Penicillin-resistant pneumococci

Journal of Hospital Infection, 1991
Penicillin-resistant pneumococci were first reported in Australia in 1967 and appeared in the UK in 1976. Their prevalence is increasing but varies greatly worldwide. The mechanism of resistance lies in the alteration of penicillin-binding proteins. Penicillin-resistant strains are often also resistant to a variety of non-beta-lactam antibiotics.
openaire   +3 more sources

Resistant penicillin-binding proteins

Cellular and Molecular Life Sciences CMLS, 1998
Low-affinity penicillin-binding proteins (PBPs), which participate in the beta-lactam resistance of several pathogenic bacteria, have different origins. Natural transformation and recombination events with DNA acquired from neighbouring intrinsically resistant organisms are responsible for the appearance of mosaic genes encoding two or three low ...
R, Hakenbeck, J, Coyette
openaire   +2 more sources

A penicillin-resistant pneumococcus

The Journal of Pediatrics, 1978
STREPTOCOCCUS PNEUMONIAE has been almost uniformly sensitive to pen!cillin, With minimum inhibitory concentrations of 0.05 Fg/m 1 or less. In 1967, the first pariially resistant strain with an MIC of 0.6/~g/ml, was reported from Sydney, Australia. Since then there have been reports of pneumococci having increased resistance to penicillin, with MICs ...
K L, Cates, J M, Gerrard, G S, Giebink, M E, Lund, E Z, Bleeker, S, Lau, M C, O'Leary, W, Krivit, P G, Quie   +8 more
openaire   +2 more sources

Penicillin Resistance and Aminoglycoside-Penicillin Synergy in Enterococci

Chemotherapy, 1995
Susceptibility to penicillin, vancomycin, imipenem, streptomycin, kanamycin and gentamicin was tested in 130 clinical isolates of Enterococcus spp. by an agar dilution method. Penicillin resistance (MIC > 8 mg/l) was only observed among strains of Enterococcus faecium and Enterococcus raffinosus.
H A, Lopardo, M E, Venuta, E A, Rubeglio
openaire   +2 more sources

Penicillin-resistant Staphylococci*

American Journal of Clinical Pathology, 1949
W G, RICE, A M, LONERGAN
openaire   +3 more sources

Penicillin-Resistant Staphylococci

JAMA: The Journal of the American Medical Association, 1974
To the Editor.— In the recent article by Ross et al (229:1075, 1974), 84% of the staphylococcal ( Staphylococcus aureus ) isolates from community-acquired infections in children were found to be resistant to penicillin. This is similar to our findings in an adult population.
openaire   +1 more source