Results 331 to 340 of about 3,443,339 (411)

Biodegradable and Implantable Triboelectric Nanogenerator Improved by β‐Lactoglobulin Fibrils‐Assisted Flexible PVA Porous Film

open access: yesAdvanced Science, EarlyView.
BF‐PVA porous film is prepared by doping BF into PVA to form hydrogel and then freeze‐drying and compression to improve the tensile resistance, bending resistance, swelling resistance, degradation time and electrical properties of PVA. Finally, the degradable triboelectric sensor made of BF‐PVA porous film and Mg film is used to realize the signal ...
Yichang Quan   +11 more
wiley   +1 more source

DNA Origami‐Cyanine Nanocomplex for Precision Imaging of KRAS‐Mutant Pancreatic Cancer Cells

open access: yesAdvanced Science, EarlyView.
DNA origami‐cyanine (Do‐Cy) nanocomplexes are synthesized to selectively image KRAS‐mutant pancreatic cancer cells in the highly desmoplastic tumors. This study shows that the Do‐Cy nanocomplexes are preferentially internalized by cancer cells over other stroma cells via KRAS‐dependent macropinocytosis.
Hye‐ran Moon   +7 more
wiley   +1 more source

Injectable pH Responsive Conductive Hydrogel for Intelligent Delivery of Metformin and Exosomes to Enhance Cardiac Repair after Myocardial Ischemia‐Reperfusion Injury

open access: yesAdvanced Science, EarlyView.
Injectable pH responsive conductive hydrogel for intelligent delivery of metformin and exosomes to alleviate myocardial ischemia‐reperfusion injury. The hydrogel responds to the weakly acidic microenvironment of ischemic injury and can significantly reduce the production of intracellular ROS and enhance cardiac conduction, thereby resisting apoptosis ...
Nianlan Cheng   +11 more
wiley   +1 more source

Conjugated Lithocholic Acid Activates Hepatic TGR5 to Promote Lipotoxicity and MASLD‐MASH Transition by Disrupting Carnitine Biosynthesis

open access: yesAdvanced Science, EarlyView.
Takeda G protein‐coupled receptor 5 (TGR5) serves as a central regulator in the metabolic dysfunction‐associated steatotic liver disease (MASLD)/metabolic dysfunction‐associated steatohepatitis (MASH) transition via conjugated lithocholic acid (LCA). Mechanistically, TGR5 orchestrates lipotoxicity‐induced cell death through its interaction with CD36 ...
Senlin Lian   +10 more
wiley   +1 more source

Antigen‐Targeting Inserted Nanomicelles Guide Pre‐Existing Immunity to Kill Head and Neck Cancer

open access: yesAdvanced Science, EarlyView.
This study introduces a tumor‐targeted nanomicelle platform (preS1‐pHLIP) that exploits pre‐existing antiviral immunity to combat heterogeneous cancers. By delivering viral antigens to label tumors as virus‐like targets, the nanomicelles activate antiviral B and T cells, triggering in situ tumor lysis.
Lizhuo Zhang   +16 more
wiley   +1 more source

Delivery of A Chemically Modified Noncoding RNA Domain Improves Dystrophic Myotube Function

open access: yesAdvanced Science, EarlyView.
CYTOR is a pro‐myogenic ncRNA in skeletal muscle. Here, chemical probing of CYTOR, coupled with functional cellular assays identifies exon 2 as an independent myogenic RNA domain. Chemical engineering of CYTOR exon 2 RNA improves pharmacologic properties, including RNA stability and cell‐autonomous immunogenicity.
Zeinabou Niasse‐Sy   +6 more
wiley   +1 more source

Back to the future? Drastic drop in serotype 19A carriage in daycare centers within two years after a second switch to PCV13 in Belgium. [PDF]

open access: yesHum Vaccin Immunother
Ekinci E   +11 more
europepmc   +1 more source

Resistance of Streptococcus pneumoniæ to penicillin

open access: gold, 2002
Lily Contreras M   +5 more
openalex   +1 more source

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