The Circadian Clock Gene Period1 Connects the Molecular Clock to Neural Activity in the Suprachiasmatic Nucleus. [PDF]
The neural activity patterns of suprachiasmatic nucleus (SCN) neurons are dynamically regulated throughout the circadian cycle with highest levels of spontaneous action potentials during the day.
Block, Gene D +2 more
core +1 more source
Structure-based Discovery of Novel Small Molecule Wnt Signaling Inhibitors by Targeting the Cysteine-rich Domain of Frizzled. [PDF]
Frizzled is the earliest discovered glycosylated Wnt protein receptor and is critical for the initiation of Wnt signaling. Antagonizing Frizzled is effective in inhibiting the growth of multiple tumor types.
Baday, Yiressy C +9 more
core +2 more sources
EVOLUTION OF THE CIRCADIAN CLOCK IN EXTREME ENVIRONMENT: LESSONS FROM CAVEFISH. [PDF]
Evolution has been strongly influenced by the daily cycles of temperature and light imposed by the rotation of the Earth. Fascinating demonstrations of this are seen in extreme environments such as caves where some animals have remained completely ...
Cavallari, Nicola
core
Abstract A reverse-phase liquid chromatographic method is described for the assay of penicillin V potassium in tablets and powders for oral solution. Under isocratic conditions, the combined use of an octadecjrlsilane column, with a mobile phase composed of acetonitrile-methanol- O.OlM monobasic potassium phosphate (21 + 4 + 75, v/v ...
openaire +2 more sources
The relationship between apamin binding and channel block in KCa2 potassium channels. [PDF]
Small conductance calcium-activated potassium channels (KCa2.1,2.2,2.3) are widely distributed throughout the body and are involved in diverse physiological processes including the regulation of neuronal firing and smooth muscle contraction.
Benton, DCH +3 more
core
Cellular properties of convulsant-treated rat neo-cortical neurons during postnatal development [PDF]
Hablitz, John H. +3 more
core +1 more source
Effect of Five Antibiotics in Varying Concentrations on Growth of Young Corn Plants [PDF]
The products of microorganisms collectively known as antibiotics, have been investigated extensively as aids to medical sciences, but they have not been thoroughly studied for possible other uses.
Harris, William E.
core +1 more source
Antibiotic Susceptibility of Black-Pigmented \u3cem\u3eBacteroides\u3c/em\u3e Isolates from the Human Oral Cavity [PDF]
The minimal inhibitory concentrations of penicillin and six other antibiotics were determined for 66 oral black-pigmented Bacteroides isolates by using the National Committee for Clinical Laboratory Standards proposed standard agar dilution technique ...
Hohenfeldt, Paul R. +2 more
core +1 more source
Individual IKs channels at the surface of mammalian cells contain two KCNE1 accessory subunits. [PDF]
KCNE1 (E1) β-subunits assemble with KCNQ1 (Q1) voltage-gated K(+) channel α-subunits to form IKslow (IKs) channels in the heart and ear. The number of E1 subunits in IKs channels has been an issue of ongoing debate.
Dai, Hui +3 more
core
Isolation, Screening, and Characterization of Antibiotic-Degrading Bacteria for Penicillin V Potassium (PVK) from Soil on a Pig Farm. [PDF]
Yang X +6 more
europepmc +1 more source

