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Penicillin and semisynthetic penicillins in dermatology [PDF]
Penicillins are one of most important antibiotics groups. They are extremely effective and still widely used. Moreover, they are the drugs of choice for a large number of infectious diseases. Penicillins belong to the -lactam group, which also include cephalosporins, monobactams, and carbapenems.
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Mayo Clinic Proceedings, 1987
The penicillins as a group are the most frequently and widely used of the antimicrobial agents because they are effective, low in toxicity, and relatively inexpensive. Effectiveness is due to the bactericidal action, the excellent distribution throughout the body spaces, and the wide spectrum of activity.
A J, Wright, C J, Wilkowske
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The penicillins as a group are the most frequently and widely used of the antimicrobial agents because they are effective, low in toxicity, and relatively inexpensive. Effectiveness is due to the bactericidal action, the excellent distribution throughout the body spaces, and the wide spectrum of activity.
A J, Wright, C J, Wilkowske
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New England Journal of Medicine, 1963
THE opening statement of Sir Alexander Fleming's1 paper describing his initial investigations of penicillin is as follows: While working with staphylococcus variants a number of culture-plates were...
Maxwell Finland, Jerome O. Klein
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THE opening statement of Sir Alexander Fleming's1 paper describing his initial investigations of penicillin is as follows: While working with staphylococcus variants a number of culture-plates were...
Maxwell Finland, Jerome O. Klein
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Poly(2-oxazoline)-Antibiotic Conjugates with Penicillins.
Bioconjugate chemistry, 2017The conjugation of antibiotics with polymers is rarely done, but it might be a promising alternative to low-molecular-weight derivatization. The two penicillins penicillin G (PenG) and penicillin V (PenV) were attached to the end groups of different ...
Martin Schmidt+7 more
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Obstetrics and Gynecology Clinics of North America, 1992
The penicillins have played a major role in the treatment of many obstetric and gynecologic infections. The advent of the newer broad-spectrum penicillins has allowed their use as single-agent therapy for certain infections. Although toxicity is extremely low, disadvantages of their use include superinfection and induction of resistance.
B A, Campbell, S M, Cox
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The penicillins have played a major role in the treatment of many obstetric and gynecologic infections. The advent of the newer broad-spectrum penicillins has allowed their use as single-agent therapy for certain infections. Although toxicity is extremely low, disadvantages of their use include superinfection and induction of resistance.
B A, Campbell, S M, Cox
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Electrochemical behaviour of several penicillins at high potential
, 2017Electrochemical oxidation at high potential, using a bare boron-doped diamond electrode as the working electrode was evaluated for five penicillins: oxacillin, penicillin V, penicillin G, ampicillin and amoxicillin.
Bogdan Feier+3 more
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Cephalosporin and penicillin cross-reactivity in patients allergic to penicillins.
International journal of clinical pharmacology and therapeutics, 2011BACKGROUND Bata-lactam antibiotics are the most commonly used antibiotics which usually cause serious IgE-mediated allergic reactions. Of all bata-lactam antibiotics, penicillins have so far been the best-studied, but the studies of cephalosporins and ...
X.-D. Liu, N. Gao, Hailing Qiao
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Current Medicinal Chemistry, 2010
Semi-synthetic β-lactamic antibiotics are the most used anti-bacteria agents, produced in hundreds tons/year scale. It may be assumed that this situation will even increase during the next years, with new β-lactamic antibiotics under development.
G. Volpato+2 more
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Semi-synthetic β-lactamic antibiotics are the most used anti-bacteria agents, produced in hundreds tons/year scale. It may be assumed that this situation will even increase during the next years, with new β-lactamic antibiotics under development.
G. Volpato+2 more
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Journal of Organic Chemistry, 2008
The tendency for carbocyclic analogues of penicillins to undergo hydrate and hemiketal formation is central to their ability to function as beta-lactamase inhibitors.
J. Johnson+7 more
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The tendency for carbocyclic analogues of penicillins to undergo hydrate and hemiketal formation is central to their ability to function as beta-lactamase inhibitors.
J. Johnson+7 more
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