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Isolation and Molecular Characterization of Indigenous Penicillium chrysogenum/rubens Strain Portfolio for Penicillin V Production [PDF]

open access: yesMicroorganisms, 2023
Beta (β)-lactam antibiotic is an industrially important molecule produced by Penicillium chrysogenum/rubens. Penicillin is a building block for 6-aminopenicillanic acid (6-APA), an important active pharmaceutical intermediate (API) used for semi ...
Amol M. Sawant   +2 more
doaj   +2 more sources

Omics-Based Comparison of Fungal Virulence Genes, Biosynthetic Gene Clusters, and Small Molecules in Penicillium expansum and Penicillium chrysogenum [PDF]

open access: yesJournal of Fungi
Penicillium expansum is a ubiquitous pathogenic fungus that causes blue mold decay of apple fruit postharvest, and another member of the genus, Penicillium chrysogenum, is a well-studied saprophyte valued for antibiotic and small molecule production ...
Holly P. Bartholomew   +8 more
doaj   +2 more sources

Efficient production and characterization of the novel and highly active antifungal protein AfpB from Penicillium digitatum [PDF]

open access: yesScientific Reports, 2017
Filamentous fungi encode distinct antifungal proteins (AFPs) that offer great potential to develop new antifungals. Fungi are considered immune to their own AFPs as occurs in Penicillium chrysogenum, the producer of the well-known PAF.
Sandra Garrigues   +7 more
doaj   +2 more sources

Characterization of the Gene Encoding S-adenosyl-L-methionine (AdoMet) Synthetase in Penicillium chrysogenum; Role in Secondary Metabolism and Penicillin Production [PDF]

open access: yesMicroorganisms, 2021
The filamentous fungus Penicillium chrysogenum (recently reidentified as Penicillium rubens) is used in the industrial production of the β-lactam antibiotic penicillin.
Rebeca Domínguez-Santos   +7 more
doaj   +2 more sources

Penicillium chrysogenum, a Vintage Model with a Cutting-Edge Profile in Biotechnology [PDF]

open access: yesMicroorganisms, 2022
The discovery of penicillin entailed a decisive breakthrough in medicine. No other medical advance has ever had the same impact in the clinical practise. The fungus Penicillium chrysogenum (reclassified as P.
Francisco Fierro   +4 more
doaj   +2 more sources

Bio-guided discovery of antibacterial metabolites from Penicillium chrysogenum [PDF]

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry
Bio-guided isolation from the Red Sea-derived Penicillium chrysogenum yielded two new metabolites, 15-deoxy-15-amino-citreohybridonol (6) and chrysogenotoxin (7), alongside five known compounds: emodin (1), chrysophanol (2), bis(2-ethylhexyl) phthalate ...
Amira Mira   +6 more
doaj   +2 more sources

Intestinal invasion and disseminated disease associated with Penicillium chrysogenum [PDF]

open access: yesAnnals of Clinical Microbiology and Antimicrobials, 2005
Background Penicillium sp., other than P. marneffei, is an unusual cause of invasive disease. These organisms are often identified in immunosuppressed patients, either due to human immunodeficiency virus or from immunosuppressant medications post ...
Herchline Thomas E   +2 more
doaj   +3 more sources

Antibacterial Activity of Culture Extracts of Penicillium chrysogenum PCL501: Effects of Carbon Sources [PDF]

open access: yesOnline Journal of Health & Allied Sciences, 2009
Penicillium chrysogenum PCL501 produced β-lactam antibiotics when fermented with different agro-wastes: cassava shavings, corncob, sawdust and sugarcane pulp.
Blessing M. Onyegeme-Okerenta   +3 more
doaj   +3 more sources

Enhancing wheat resilience to salinity: the role of endophytic Penicillium chrysogenum as a biological agent for improved crop performance [PDF]

open access: yesBMC Plant Biology
Salinity stress severely impacts wheat productivity, necessitating effective strategies to enhance crop resilience. This study investigates the potential of Penicillium chrysogenum CM022 as a biological agent to alleviate the impact of salinity stress on
Soheila Aghaei Dargiri   +2 more
doaj   +2 more sources

Phenotypic features and molecular study of airborne Penicillium species isolated in the northern part of the Persian Gulf, Bushehr, Iran [PDF]

open access: yesCurrent Medical Mycology, 2021
Background and Purpose: The main environmental saprobes, such as Penicillium, play an essential role in natural ecosystems as economically, ecologically, and medically important microorganisms. Biodiversity of this genus has not been described in Bushehr
Behrouz Naeimi   +7 more
doaj   +1 more source

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