Results 121 to 130 of about 5,126 (297)

Albumin‐Bound STING Agonist Reprograms HSPCs to Antitumor Neutrophils Enhancing CD8+ T Cell Immunity

open access: yesAdvanced Science, EarlyView.
This study demonstrates that an albumin‐bound STING agonist (Nano ZSA‐51D) reprograms HSPCs to produce antitumor neutrophils with enhanced MHC I–mediated CD8+ T cell activation, thereby sensitizing tumors to α‐PD1 therapy. These findings highlight a strategy to target early hematopoiesis for shaping neutrophil fate and potentiating cancer immunotherapy.
Jinsong Tao   +11 more
wiley   +1 more source

The Scope of Medicare Reimbursement for New Medical Devices: Impact on Device Availability and the Standard of Care [PDF]

open access: yes, 2012
Evolving standards of care motivated by advances in medical technology alter the characteristics and costs of delivered health care. Faced with shifting reimbursement demands, the Health Care Financing Administration (HCFA) has promulgated regulations ...
Yeon, Susan B.
core  

A Conformal Wearable Ultrasound Bioelectronics for Mechanotherapy Reprogramming of Fibroblast Plasticity via Wnt‐FGF10 Axis to Overcome Fibrotic Healing in Urethral Regeneration

open access: yesAdvanced Science, EarlyView.
Fibrotic scarring persistently challenges urethral reconstruction. This study introduces a conformal, wearable ultrasound bioelectronic system that overcomes this by reprogramming fibroblast fate. The device activates a developmental Wnt–FGF10 axis, driving fibroblasts toward a regenerative FGF10+ phenotype that promotes angiogenesis and matrix ...
Mingming Yu   +7 more
wiley   +1 more source

Conformationally Driven Dual Fluorescence Properties of Higher Heteroacenes With Periodically Incorporated Boron Atoms

open access: yesAngewandte Chemie, EarlyView.
We herein report the synthesis of a new heteroheptacene derivative with periodically incorporated six boron atoms. This compound exhibits dual fluorescence attributed to two interconvertible conformers that result from a delicate balance between the extended π‐system and the steric demand of bulky aryl groups attached to the boron centers.
Takeshi Yokochi   +6 more
wiley   +2 more sources

Optical cuff for optogenetic control of the peripheral nervous system [PDF]

open access: yes, 2017
OBJECTIVE: Nerves in the peripheral nervous system (PNS) contain axons with specific motor, somatosensory and autonomic functions. Optogenetics offers an efficient approach to selectively activate axons within the nerve. However, the heterogeneous nature
Asboth, L   +8 more
core  

Organic Thin‐Film Transistors for Neuromorphic Computing

open access: yesAdvanced Electronic Materials, EarlyView.
Organic thin‐film transistors (OTFTs) are reviewed for neuromorphic computing applications, highlighting their power‐efficient, and biological time‐scale operation. This article surveys OFET and OECT devices, compares them with memristors and CMOS, analyzes how fabrication parameters shape spike‐based metrics, proposes standardized characterization ...
Luke McCarthy   +2 more
wiley   +1 more source

A scoping review of penile implant biofilms-what do we know and what remains unknown? [PDF]

open access: yesTransl Androl Urol, 2022
Leong JY   +10 more
europepmc   +1 more source

Embedded Direct‐Written Organic Micro‐TEGs for High‐Efficiency Skin‐Heat Harvesting

open access: yesAdvanced Electronic Materials, EarlyView.
A finite‐element–guided design of direct‐written organic micro‐thermoelectric generators is presented for efficient skin‐heat harvesting. Embedding PEDOT:PSS/PBFDO thermoelectric legs within flexible substrates suppresses interfacial heat losses and enhances vertical heat flow.
Milad Jabri   +4 more
wiley   +1 more source

Malleable Penile Implant Rod Diameter Predicts Complications and Patient Satisfaction. [PDF]

open access: yesSex Med, 2022
Habous M   +8 more
europepmc   +1 more source

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