Prevalence and sequelae of penile lichen sclerosus in males presenting for circumcision in regional Australia: a multicentre retrospective cohort study [PDF]
Background: Lichen sclerosus (LS) in men commonly involves the external genitalia, with up to 20% of these patients developing urethral stricture disease, and a small group developing malignant transformation to penile squamous cell carcinoma (SCC).
Bandi, S +8 more
core +2 more sources
Engineered GM1 Intersects Between Mitochondrial and Synaptic Pathways to Ameliorate ALS Pathology
Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease driven by genetic and molecular disruptions affecting energy balance, protein homeostasis, and stress responses in nerve cells. Studies using human and rodent models identified convergent defects in mitochondria and synaptic function.
Federica Pilotto +11 more
wiley +1 more source
Partial Priapism Treated with Pentoxifylline
Main findings:A 26-year-old man suffering from partial priapism was successfully treated with a regimen including pentoxifylline, a nonspecific phosphodiesterase inhibitor that is often used to conservatively treat Peyronie's disease.Case hypothesis ...
Meghan A. Cooper +2 more
doaj +1 more source
The Efficacy of Medical Treatment of Peyronie’s Disease: Potassium Para-Aminobenzoate Monotherapy vs. Combination Therapy with Tamoxifen, L-Carnitine, and Phosphodiesterase Type 5 Inhibitor [PDF]
Purpose: This study was designed to evaluate the efficacy of medical treatment of Peyronie’s disease. Materials and Methods: A total of 109 patients with Peyronie’s disease who had been treated from January 2011 to December 2014 were retrospectively ...
Tae Yong Park +8 more
doaj +1 more source
Surgical treatment of penile curvature [PDF]
OBJECTIVE: To review long-term efficacy and complications of surgical treatment of penile curvature in a Chinese population. DESIGN: Retrospective review. SETTING: Regional hospital, Hong Kong. PATIENTS.
Ho, KL, Law, IC, Leung, LS, Yip, AWC
core
Genital Human Papillomavirus (HPV) Infections in Men as a Factor for the Development of Cervical Cancer [PDF]
The prevalence of human papillomavirus (HPV) infection in males is comparable to females, although in men it is largely unknown. HPV infections may be connected with the development of carcinomas and other dermoepithelial changes such as intraepithelial ...
Chalasinski, Jack +3 more
core +1 more source
Computational annotation of various tissue types in heterogeneous samples such as colorectal cancer liver metastasis (CRLM) using spatial autocorrelation analysis on non‐destructive mid‐infrared (MIR) imaging data enabled correlative multimodal mass spectrometry imaging (MSI) for spatial investigation of lipid tumor marker candidates. The method can be
Miriam F. Rittel +12 more
wiley +1 more source
Nonsurgical treatment options in Peyronie’s Disease: 2016 update
Peyronie’s disease (PD) is an inflammatory condition of penile tunica albuginea which commonly ends with penile curvature and difficulty in vaginal penetration. Unfortunately, the pathophysiology of PD has not been completely understood.
Raidh A. Talib +2 more
doaj +1 more source
ヒト陰茎扁平上皮癌培養細胞株TSUS-1の樹立とその性状 [PDF]
37歳男性の電撃型陰茎癌患者の転移を認めた心嚢液よりヒト陰茎扁平上皮癌培養細胞株TSUS-1を樹立した.継代培養は60代におよび2年5ヵ月を経過した現在なお増殖を続けており, ヌードマウス皮下移植率は100%であった.継代培養40代の染色体分析でモード75の低四倍体で, マーカー染色体を7個認めた.ヌードマウス移植腫瘍は皮膚に浸潤し, 角化傾向も著明で, 原発巣の陰茎癌類似の肉眼的所見を示し, 組織学的には癌真珠を含む角化傾向を散見する扁平上皮癌で, 原発陰茎癌に類似していたWe established
Ishikawa, Satoru +2 more
core
Equine models in translational medicine: A comparative approach to human health
This diagram summarizes and contrasts rodent and equine models, outlining their strengths, limitations, and applications. Horses offer naturally occurring diseases, genetic and physiological similarities to humans, and suitability for longitudinal and clinical‐scale studies.
Shayan Boozarjomehri Amnieh +1 more
wiley +1 more source

