Results 111 to 120 of about 5,528 (259)

Imatinib decreases germ cell survival and germline stem cell proliferation in rodent testis ex vivo and in vitro

Andrology, EarlyView.
Abstract Background Imatinib and dasatinib are tyrosine kinase inhibitors (TKIs) increasingly used to treat several diseases in both children and adults at fertile age. We have previously shown that imatinib has adverse effects on developing testis, and imatinib‐treated male patients have been reported to have reduced sperm counts.
Anna Eggert, Sini Laasanen, Mirja Nurmio, Aida Wahlgren, Kirsi Jahnukainen, Kim Eerola, Miisael Nieminen, Opeyemi Olotu, Noora Kotaja, Juho‐Antti Mäkelä, Jorma Toppari   +10 more
wiley   +1 more source

Therapeutic potential of hesperidin in diabetes mellitus‐induced erectile dysfunction through Nrf2‐mediated ferroptosis and oxidative stress

Andrology, EarlyView.
Abstract Background Among erectile dysfunction (ED) caused by metabolic abnormalities, diabetes mellitus‐induced ED (DMED) progresses rapidly, manifests with severe symptoms, and shows reduced responsiveness to conventional medications. Hyperglycemia in the corpus cavernosum has been linked to the induction of both ferroptosis and oxidative stress ...
Sheng Xin, Wen Song, Jiaquan Mao, Peng Hu, Zhong Chen, Jihong Liu, Xiaodong Song, Qian Fang, Kai Cui   +8 more
wiley   +1 more source

External validation of nomogram to predict inguinal lymph node metastasis in patients with penile cancer and clinically negative lymph nodes

International Brazilian Journal of Urology
Introduction Penile cancer (PC) occurs less frequently in Europe and in the United States than in South America and parts of Africa. Lymph node (LN) involvement is the most important prognostic factor, and inguinal LN (ILN) dissection can be curative ...
Carlos Vaz de Melo Maciel, Roberto Dias Machado, Mariana Andozia Morini, Pablo Aloisio Lima Mattos, Ricardo dos Reis, Rodolfo Borges dos Reis, Gustavo Cardoso Guimarães, Isabela Werneck da Cunha, Eliney Ferreira Faria   +8 more
doaj   +1 more source

Prevalence of HPV infection in the general population of young and adult males in Italy

Andrology, EarlyView.
Abstract Background The most prevalent sexually transmitted disease in the world has the human papillomavirus (HPV) as its etiological agent. Objectives To evaluate the prevalence of previous and actual HPV infection and the clinical manifestations in unselected males.
Giuseppe Grande, Andrea Graziani, Luca De Toni, Federica Finocchi, Adriano Presciutti, Sara Corrò, Alberto Ferlin, Andrea Garolla   +7 more
wiley   +1 more source

Intracardiac metastasis of squamous cell carcinoma of the penis

Autopsy and Case Reports, 2013
Penile cancer shows variable incidence in different countries with a higher prevalence in developing countries. Squamous cell carcinoma represents the most common histologic type.
Sheila Aparecida Coelho Siqueira, Camila Satie Tomikawa   +1 more
doaj  

Feasibility of partial penectomy under local anesthesia: a case–control study

African Journal of Urology
Background To assess the feasibility of partial penectomy under local anesthesia and penile nerve blocks. Methods A total of 45 patients underwent partial penectomy under local anesthesia over the last 15 years at our institute.
Madhur Anand, Apul Goel, Bhupendra Pal Singh, Swati Aggarwal, Manoj Kumar, Vivek Kumar Singh, Vishwajeet Singh   +6 more
doaj   +1 more source

Risk of priapism after dynamic penile Doppler ultrasound: Single‐centre experience on a large cohort of patients

Andrology, EarlyView.
Abstract Objectives To evaluate the risk of priapism in patients undergoing Dynamic—Penile duplex ultrasound (D‐PDU) who were referred to our Unit between January 2022 and December 2023. Patients and methods We enrolled 292 patients, of whom 268 underwent Dynamic—Penile duplex ultrasound for erectile dysfunction and 24 for Peyronie's disease.
Giuseppe Grande, Andrea Graziani, Raffaele Scafa, Andrea Delbarba, Nicola Caretta, Pierfrancesco Palego, Alberto Ferlin   +6 more
wiley   +1 more source

Detection of germ cell neoplasia in situ and testicular cancer risk in men with testicular microlithiasis: Real world results through 10 years

Andrology, EarlyView.
Abstract Background Guidelines recommend biopsies for men <50 years with testicular microlithiasis and cancer risk factors to rule out germ cell neoplasia in situ. Limited data support this practice. Objectives To clarify the significance of testicular microlithiasis by examining pathological findings in men with testicular microlithiasis.
Karoline Skov Lundager, Rasmus Hassing Frandsen, Emil Durukan, Nadia Zeeberg Belhouche, Christian Fuglesang S. Jensen, Peter Busch Østergren, Jens Sønksen, Mikkel Fode   +7 more
wiley   +1 more source

Association of bi‐parametric MRI measures with continence after robot‐assisted radical prostatectomy

BJU International, Volume 135, Issue 4, Page 603-610, April 2025.
Objective To investigate the association between pre‐ and postoperative magnetic resonance imaging (MRI) measurements of the membranous urethra and the prostate volume and continence following robot‐assisted radical prostatectomy (RARP). Patients and Methods From December 2018 to June 2022, 100 continent patients undergoing unilateral nerve‐sparing or ...
Alexander B. Nolsøe, Vibeke Løgager, Lars Boesen, Peter Busch Østergren, Henrik Jakobsen, Christian Fuglesang S. Jensen, Niels Henrik Bruun, Jens Sønksen, Mikkel Fode   +8 more
wiley   +1 more source

Retrospective clinical and molecular characterisation of patients with penile intraepithelial neoplasia

BJU International, EarlyView.
Objectives To provide the first comprehensive molecular characterisation of penile intraepithelial neoplasia (PeIN) and to define the molecular alterations and clinical parameters associated with recurrence in order to enhance our ability to manage this disease.
Sara Kaczor Elbæk, Philippe Lamy, Simen Laugesen, Christina Stilling, Iver Nordentoft, Lars Dyrskjøt, Jakob Kristian Jakobsen   +6 more
wiley   +1 more source