Results 141 to 150 of about 388,358 (308)

LKB1 Loss Sensitizes Lung Tumor Spheres to Mitomet‐Induced Ferroptosis, and These Effects are Enhanced by mTOR Inhibition

Molecular Carcinogenesis, EarlyView.
ABSTRACT Owing to their robust antioxidant defense mechanisms, cancer stem‐like cells (CSCs) maintain a low level of oxidative stress, which is crucial for preserving stemness and pluripotency. Therefore, agents that either directly generate reactive oxygen species (ROS) or inhibit the antioxidant defense systems can selectively induce oxidative cell ...
Xueqing Liang, Ali Nakhi, Peter I. Dosa, Gunda I. Georg, Fekadu Kassie   +4 more
wiley   +1 more source

Penile Neoplasm [PDF]

, 2020
openaire   +1 more source

Mucosal Margin Shrinkage in Oral Cavity Cancer: A Systematic Review

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective Tissue shrinkage can make planning of surgical margins challenging. While shrinkage of resected oral cavity mucosa is well‐described, current data quantifying these effects are variable. The aim of this systematic review was to summarize current evidence on margin shrinkage in oral cavity cancer after resection and formalin fixation.
Sindhura Sridhar, Daniel P. Larson, Michael C. Topf   +2 more
wiley   +1 more source

Automated quality assurance of HDR brachytherapy: Evaluation of Dwell‐position accuracy and Dwell‐time linearity via image processing of radiochromic films

Precision Radiation Oncology, EarlyView.
This study develops a method combining radiochromic film and image processing to assess HDR brachytherapy source accuracy and linearity, achieving high precision and efficiency . Abstract Purpose To develop and validate a fully automated quality assurance method for high‐dose rate (HDR) brachytherapy, enabling the precise evaluation of source dwell ...
Qingqing Yuan, Suyan Bi, En Lou, YaJun Jia, Zhitao Dai   +4 more
wiley   +1 more source

What is new in Genitourinary Pathology? Recent developments and highlights of the new 2016 World Health Organization classification of tumors of the urinary system and male genital organs [PDF]

, 2016
Daniel Abensur Athanazio, Kiril Trpkov
core   +1 more source

In Silico Structure‐Guided Design of Peptide Candidates Targeting γ‐Secretase Subunit Assembly

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT The γ‐secretase complex is a membrane‐embedded protease essential for intramembrane cleavage of substrates such as Notch receptors and the amyloid precursor protein (APP), processes central to cancer progression and Alzheimer's disease (AD) pathology.
Selcen Arı Yuka, Kübra Telli, Alper Yılmaz   +2 more
wiley   +1 more source

Spongiosolysis [PDF]

, 1987
Gilbert, P., Stief, Christian Georg
core   +1 more source

Variation on Toxic and Inflammatory Potential of Coal Smoke of Different Sources From a Region With High Lung Cancer Risk

Environmental Toxicology, EarlyView.
ABSTRACT Excess lung cancer risk in Xuanwei and Fuyuan, China, has been attributed to household air pollution from use of a locally sourced smoky (bituminous) coal. However, the carcinogenic mechanisms remain unclear. Given the important role of inflammation in lung cancer development, this study compared the proinflammatory potentials of the ...
Yongliang Zhang, Wei Hu, Nathanial Rothman, Dingyu Liu, Jihua Li, Jun Xu, Bofu Ning, Roel Vermeulen, Qing Lan, Flemming R. Cassee, George S. Downward   +10 more
wiley   +1 more source

Functional evaluation of penile hemodynamics [PDF]

, 1988
Bookstein, Brindley, Buvat, Ek, Jevtich, Juenemann, Jünemann, Karacan, Kockott, Lue, Lue, Newman, Porst, Sidi, Stief, van Arsdalen, Virag, Virag, Virag, Virag, Zorgniotti   +20 more
core   +1 more source

Benign Penile Neoplasm [PDF]

, 2020
openaire   +1 more source